| Proje Ekibi |
Dr. Öğr. Üyesi Fatih UĞUR
Kastamonu Üniversitesi, Türkiye Projedeki Rolü: Yürütücü |
| Proje Türü | BAP Proje |
| Proje No | - |
| Proje Konusu | Total Knee arthroplasty(TKA) surgery is a common treatment option for advanced knee osteoarthritis. The aim of this surgery is to reduce pain and improve function. Knee prostheses are generally divided into two main types: prostheses where the PCL is retained and prostheses where the PCL is removed (or replaced). When TKA is performed, the decision to retain or remove the PCL is based on preoperative clinical findings or intraoperative findings. It is known that degeneration in the PCL affects the outcomes of TKA The limited number of studies demonstrating the relationship between PCL degeneration and OA, along with the inclusion of differences in osteoarthritis classification and mild osteoarthritis patients, indicate a lack of sufficient scientific data. Articular ligaments are generally less strong and rigid, and their biomechanical properties depend on collagen fibrils. Previous studies have not found a relationship between the condition of the ACL and degeneration of the PCL. However, these findings contradict the findings of other studies. The consideration of classifications used to evaluate the degree of osteoarthritis in patients and histopathological examination of the PCL necessitate further comprehensive research on this topic. In this study, histopathological evaluation of the PCL and the presence of ACL were specifically examined in knee arthroplasty surgeries performed on patients with grade 3-4 osteoarthritis according to the commonly used KL classification This study focused on patients with stage 3-4 osteoarthritis who underwent knee replacement surgery at Kastamonu Training and Research Hospital. Surgeries were performed using a medial parapatellar approach, and PCL Sacrificing prostheses were applied to patients. Due to the absence of ACL in all patients, it was not included in the histological examination. The histological evaluation of PCL focused on the degree of integrity/destruction of collagen fibers and also assessed associated findings such as hypercellularity, inflamatory cell infiltration, vascular proliferation, cyst presence, chondrocyte clones, collagen, fibrinoid, cartilage, and mucoid degeneration. The results suggest that the histopathological status of PCL may provide insights for surgeons in prosthetic selection |
| Proje Durumu | Devam Ediyor |
| Başlangıç Tarihi | 02-10-2024 |
| Bitiş Tarihi |
