| Yazarlar (6) |
Zulbiye Önal
|
|
Zeynep Çimen
|
|
İlhan Özer İlhan
Erciyes Üniversitesi, Türkiye |
Prof. Dr. Fatma KANDEMİRLİ
|
|
Murat Saraçoğlu
Erciyes Üniversitesi, Türkiye |
Doç. Dr. Can Doğan VURDU
Kastamonu Üniversitesi, Türkiye |
| Özet |
| Pyrimidine derivatives show various interesting pharmacological properties including antiviral, antiparasitic, antibacterial and antitumor effects. Some of them are frequently encountered in many drugs used for the treatment of hypothyroidy, hypertension, cancer chemotherapy or HIV infection [1-2]. Recently, the reactions of 1-aminopyrimidine derivatives with several anhydrides, isocyanates and isothiocyanates have been reported [3]. We are now reporting the reaction mechanism, synthesis and characterization of novel 2-oxopyrimidin-1 (2H)-yl-amides by the reaction of the 1-aminopyrimidine-2 (1H)-one/-thione derivatives with the corresponding some acide chlorides. Calculated quantum chemical parameters such as EHOMO (highest occupied molecular orbital energy), ELUMO (lowest unoccupied molecular orbital energy), the energy difference (ΔE) between EHOMO and ELUMO, dipole moment (μ), the … |
| Anahtar Kelimeler |
| Bildiri Türü | Tebliğ/Bildiri |
| Bildiri Alt Türü | Özet Metin Olarak Yayınlanan Tebliğ (Uluslararası Kongre/Sempozyum) |
| Bildiri Niteliği | Alanında Hakemli Uluslararası Kongre/Sempozyum |
| Bildiri Dili | İngilizce |
| Kongre Adı | The 2nd International Conference on Computation for Science and Technology |
| Kongre Tarihi | 09-07-2012 / 11-07-2012 |
| Basıldığı Ülke | Türkiye |
| Basıldığı Şehir | Niğde |
