| Yazarlar |
Begüm Öktem
|
|
Fatih Üzer
Akdeniz Üniversitesi, Türkiye |
Prof. Dr. Fatma Mutlu KUKUL GÜVEN
Kastamonu Üniversitesi, Türkiye |
|
İdris Kırhan
Harran Üniversitesi, Türkiye |
|
Mehmet Topal
Kastamonu Üniversitesi, Türkiye |
| Özet |
| World Health Organization has declared coronavirus disease-19 (COVID-19) as a pandemic. Although there are studies about this novel virus, our knowledge is still limited. There is limited information about its diagnosis, treatment and prognosis. We aimed to investigate the effect of methemoglobin and carboxyhemoglobin levels on the prognosis of COVID-19. In this observational study, patients who were diagnosed with COVID-19 during March 1-April 31, 2020 in a secondary-level state hospital in Turkey were included in the study. COVID-19 diagnosis was confirmed with reverse transcription polymerase chain reaction method, with nasal, oral or sputum specimens. During the period this study was performed, 3075 patients were tested for COVID-19 and 573 of them were hospitalized. Among the hospitalised patients, 23.2% (133) of them had a positive polymerase chain reaction result for COVID-19. A total of 125 patients, 66 (52.8%) males and 59 (47.2%) females, with an average age of 50.2 ± 19.8 years, were included in the study. The most common findings in chest radiogram were ground-glass areas and consolidations, while one-third of the patients had a normal chest radiogram. Computed thorax tomography was performed for 77.6% (97/125) of the patients. The 24.7% of computed tomographies (24/97) did not reveal any pathological findings, and the most common findings were ground-glass appearance and consolidation. Those who needed intensive care had statistically significantly lower platelet count (P = 0.011) and higher lactate dehydrogenase levels (P < 0.001). No statistically significant difference was found in carboxyhemoglobin (P = 0.395) and methemoglobin (P = 1.000) levels. We found that carboxyhemoglobin and methemoglobin levels had no effect on COVID-19 prognosis, but low platelet level played a role in predicting COVID-19 prognosis. This study was approved by the Ethical Committee of Harran University Faculty of Medicine on May 11, 2020 with approval No. 09. |
| Anahtar Kelimeler |
| carboxyhemoglobin,COVID-19,methemoglobin,pandemic,prognosis |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Medical Gas Research |
| Dergi ISSN | 2045-9912 |
| Dergi Tarandığı Indeksler | emergency science citation index |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 03-2021 |
| Cilt No | 10 |
| Sayı | 4 |
| Sayfalar | 174 / 178 |
| Doi Numarası | 10.4103/2045-9912.304224 |
| Atıf Sayıları | |
| WoS | 5 |
| SCOPUS | 4 |
