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Advancing Semen Evaluation Using Lipidomics     
Yazarlar
Holly C. Evans
Thu Tran Nhat Dinh
Madison L. Hardcastle
Alicia Gilmore
Muhammet Rasit Ugur
Doç. Dr. Mustafa HİTİT Doç. Dr. Mustafa HİTİT
Kastamonu Üniversitesi, Türkiye
Dean Jousan
Molly Nıcodemus
Erdoğan Memili
Özet
Developing a deeper understanding of biological components of sperm is essential to improving cryopreservation techniques and reproductive technologies. To fully ascertain the functional determinants of fertility, lipidomic methods have come to the forefront. Lipidomics is the study of the lipid profile (lipidome) within a cell, tissue, or organism and provides a quantitative analysis of the lipid content in that sample. Sperm cells are composed of various lipids, each with their unique contribution to the overall function of the cell. Lipidomics has already been used to find new and exciting information regarding the fatty acid content of sperm cells from different species. While the applications of lipidomics are rapidly evolving, gaps in the knowledge base remain unresolved. Current limitations of lipidomics studies include the number of available samples to analyze and the total amount of cells within those samples needed to detect changes in the lipid profiles across different subjects. The information obtained through lipidomics research is essential to systems and cellular biology. This review provides a concise analysis of the most recent developments in lipidomic research. This scientific resource is important because these developments can be used to not only combat the reproductive challenges faced when using cryopreserved semen and artificial reproductive technologies in livestock such as cattle, but also other mammals, such as humans or endangered species.
Anahtar Kelimeler
biomarkers | cryotolerance | fatty acids | lipids | livestock
Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü SCI, SSCI, AHCI, SCI-Exp dergilerinde yayımlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale
Dergi Adı FRONTIERS IN VETERINARY SCIENCE
Dergi ISSN 2297-1769
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 04-2021
Cilt No 8
Sayı 1
Doi Numarası 10.3389/fvets.2021.601794
Makale Linki http://dx.doi.org/10.3389/fvets.2021.601794
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 19
SCOPUS 24
Advancing Semen Evaluation Using Lipidomics

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