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Fiber Based Approaches as Medicine Delivery Systems      
Yazarlar
Farrokh Sharıfı
Avınash C Soorıyarachchı
Dr. Öğr. Üyesi Hayriye ALTURAL ÖZKAN Dr. Öğr. Üyesi Hayriye ALTURAL ÖZKAN
Kastamonu Üniversitesi, Türkiye
Reza Montazamı
Marıssa Nıchole Rylander
Nastaran Hashemı
Özet
The goal of drug delivery is to ensure that therapeutic molecules reach the intended target organ or tissue, such that the effectiveness of the drug is maximized. The efficiency of a drug delivery system greatly depends on the choice of drug carrier. Recently, there has been growing interest in using micro- and nanofibers for this purpose. The reasons for this growing interest include these materials' high surface area to volume ratios, ease of fabrication, high mechanical properties, and desirable drug release profile. Here, we review developments in using these materials made by the most prevalent methods of fiber fabrication: electrospinning, microfluidics, wet spinning, rotary spinning, and self-assembly for drug delivery purposes. Additionally, we discuss the potential to use these fiber based systems in research and clinical applications.
Anahtar Kelimeler
drug delivery | electrospinning | micro- and nanofiber fabrication | microfluidics | rotary spinning | self-assembly | wet spinning
Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü SCI, SSCI, AHCI, SCI-Exp dergilerinde yayımlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale
Dergi Adı ACS Biomaterials Science & Engineering
Dergi ISSN 2373-9878
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 09-2016
Cilt No 2
Sayı 9
Sayfalar 1411 / 1431
Doi Numarası 10.1021/acsbiomaterials.6b00281
Makale Linki http://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.6b00281
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
SCOPUS 89
Fiber Based Approaches as Medicine Delivery Systems

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