The importance of myeloperoxidase enzyme activity in the pathogenesis of Crimean Congo haemorrhagic fever
Yazarlar (7)
Prof. Dr. Fatma Mutlu KUKUL GÜVEN Cumhuriyet Üniversitesi, Türkiye
Prof. Dr. Hüseyin Aydın Cumhuriyet Üniversitesi, Türkiye
Gürsel Yıldız Yeni Yüzyıl Üniversitesi, Türkiye
Prof. Dr. Aynur Engin Cumhuriyet Üniversitesi, Türkiye
Prof. Dr. Veysel Kenan Çelik Cumhuriyet Üniversitesi, Türkiye
Bakır Deniz
Köksal Deveci
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | JOURNAL OF MEDICAL MICROBIOLOGY | ||
| Dergi ISSN | 0022-2615 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2013 |
| Cilt / Sayı / Sayfa | 62 / 3 / 441–445 | DOI | 10.1099/jmm.0.047589-0 |
| Makale Linki | https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.047589-0 | ||
| UAK Araştırma Alanları |
Fen Bilimleri ve Matematik
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| Özet |
| Crimean–Congo haemorrhagic fever (CCHF) is a disease with a severe course including acute viral haemorrhagic fever, ecchymosis, thrombocytopenia, hepatic function disorder and high mortality. Myeloperoxidase (MPO) is an enzyme located in neutrophil granulocytes and plays an important role in the destruction of phagocytosed micro-organisms. The aim of this study was to analyse MPO enzyme activity in CCHF cases compared with a control group. A total of 47 randomly selected CCHF patients admitted to the Department of Infectious Diseases of Cumhuriyet University Hospital in Sivas, Turkey, were studied, and as a control group, 41 age- and sex-matched individuals without any systemic disease were included in this study. MPO enzyme activity was measured in plasma and leukocytes for both groups by the ELISA method. MPO plasma and MPO leukocyte values were calculated as 57.62±8.85 and 44.84 … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
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| Web of Science | 8 |
| Google Scholar | 21 |