Synthesis and characterization of new 1,3,4-thiadiazole derivatives: study of their antibacterial activity and CT-DNA binding
Yazarlar (16)
Hakan Sayiner
Mehmet Yilmazer
Aisha Abdelsalam
Mohamed Ganim
Prof. Dr. Mehmet Cengiz BALOĞLU Kastamonu Üniversitesi, Türkiye
Prof. Dr. Yasemin ÇELİK ALTUNOĞLU Kastamonu Üniversitesi, Türkiye
Prof. Dr. Mahmut GÜR Kastamonu Üniversitesi, Türkiye
Prof. Dr. Murat Saraçoğlu Türkiye
Mohamed Attia
Safwat Mahmoud
Ekram Mohamed
Rabah Boukherroub
Nora Hamad Al-Shaalan
Sarah Alharthi
Prof. Dr. Fatma Kandemirli Kastamonu Üniversitesi, Türkiye
Mohammed Amin
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Royal Society of Chemistry (RSC) (Q2) | ||
| Dergi ISSN | 2046-2069 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2022 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-01-2022 |
| Cilt / Sayı / Sayfa | 12 / 46 / 29627–29639 | DOI | 10.1039/d2ra02435g |
| Makale Linki | http://dx.doi.org/10.1039/d2ra02435g | ||
| UAK Araştırma Alanları |
Biyoteknoloji
Moleküler Biyoloji
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| Özet |
| 1,3,4-Thiadiazole molecules (1–4) were synthesized by the reaction of phenylthiosemicarbazide and methoxy cinnamic acid molecules in the presence of phosphorus oxychloride, and characterized with UV, FT-IR, 13C-NMR, and 1H-NMR methods. DFT calculations (b3lyp/6-311++G(d,p)) were performed to investigate the structures' geometry and physiochemical properties. Their antibacterial activity was screened for various bacteria strains such as Enterobacter aerogenes, Escherichia coli ATCC 13048, Salmonella kentucky, Pseudomonas aeruginosa, Klebsiella pneumoniae, Proteus and Gram positive such as Staphylococcus aureus ATCC 25923, Listeria monocytogenes ATCC 7644, Enterococcus faecium, Enterococcus durans, Staphylococcus aureus ATCC, Serratia marcescens, Staphylococcus hominis, Staphylococcus epidermidis, alfa Streptococcus haemolyticus, Enterococcus faecium and found to have … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 29 |