Chemical fingerprints, antioxidant, enzyme inhibitory, and cell assays of three extracts obtained from Sideritis ozturkii Aytaç Aksoy: An endemic plant from Turkey
Yazarlar (10)
Gokhan Zengin Selçuk Üniversitesi, Türkiye
Asli Uğurlu Kastamonu Üniversitesi, Türkiye
Prof. Dr. Mehmet Cengiz BALOĞLU Kastamonu Üniversitesi, Türkiye
Alina Diuzheva Pavol Jozef Šafárik University İn Košice, Slovakya
József Jekő University Of Nyíregyháza, Macaristan
Zoltán Cziáky University Of Nyíregyháza, Macaristan
Ramazan Ceylan Selçuk Üniversitesi, Türkiye
Abdurrahman Aktumsek Selçuk Üniversitesi, Türkiye
Carene Marie Nancy Picot-Allain University Of Mauritius, Mauritius
M. Fawzi Mahomoodally University Of Mauritius, Mauritius
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Pharmaceutical and Biomedical Analysis (Q2) | ||
| Dergi ISSN | 0731-7085 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 04-2019 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-07-2019 |
| Cilt / Sayı / Sayfa | 171 / 1 / 118–125 | DOI | 10.1016/j.jpba.2019.04.011 |
| Makale Linki | https://www.sciencedirect.com/science/article/abs/pii/S0731708519302973?via3Dihub | ||
| Özet |
| This study was geared towards assessing the possible antioxidant, enzyme inhibitory, and cytotoxic activities of ethyl acetate, methanol, and water extracts of Sideritis ozturkii Aytaç & Aksoy. The phytochemical profiles of the studied extracts were characterised by HPLC-MS/MS. The methanol extract, rich in phenolics (78.04 mg gallic acid equivalent/g), exhibited the strongest antioxidant activities. However, the ethyl acetate extract was the most active extract in the enzyme inhibitory assays. The water extract of S. ozturkii (1 mg/ml, 48 h incubation) slightly inhibited (22%) growth of human breast cancer cell line (MDA-MB-231 cells). On the other hand, the ethyl acetate and methanol extracts showed strong inhibition (98% and 97%, respectively) of MDA-MB-231 cells and caused apoptotic cell death. Scientific data generated from this study further appraises the multiple biological activities of plants belonging to the … |
| Anahtar Kelimeler |
| Antioxidant | Apoptosis | Bioactive agents | Diabetes | Neuroprotection | Sideritis |
Science Direct
Chemical fingerprints, antioxidant, enzyme inhibitory, and cell assays of three extracts obtained from Sideritis ozturkii Aytaç Aksoy: An endemic plant from Turkey
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Scopus | 24 |
| Google Scholar | 29 |