Usefulness of admission matrix metalloproteinase 9 as a predictor of early mortality after cardiopulmonary resuscitation in cardiac arrest patients
Yazarlar (6)
Kenan Ahmet Türkdoğan
Adnan Menderes Üniversitesi, Türkiye
Adnan Menderes Üniversitesi, Türkiye
Ali Zorlu Cumhuriyet Üniversitesi, Türkiye
Prof. Dr. Fatma Mutlu KUKUL GÜVEN Cumhuriyet Üniversitesi, Türkiye
İsmail Ekinözü
Umut Eryiğit
Prof. Dr. Mehmet Birhan Yılmaz Cumhuriyet Üniversitesi, Türkiye
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Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | AMERICAN JOURNAL OF EMERGENCY MEDICINE (Q1) | ||
| Dergi ISSN | 0735-6757 Dergi Bilgileri (2012) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 11-2012 |
| Cilt / Sayı / Sayfa | 30 / 9 / 1804–1809 | DOI | 10.1016/j.ajem.2012.02.017 |
| Makale Linki | https://hdl.handle.net/20.500.12684/5328 | ||
| UAK Araştırma Alanları |
Acil Tıp
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| Özet |
| BackgroundMatrix metalloproteinases (MMPs) have a central role in disease progression after ischemia-reperfusion injury. However, its prognostic significance in cardiac arrest (CA) patients having cardiopulmonary resuscitation (CPR) is unknown. The aim of this study was to investigate the relation between admission MMP-9 level and early mortality in CA patients.MethodsA total of 96 in-hospital or out-of-hospital CA patients and 40 age- and sex-matched healthy volunteers as the control group were evaluated prospectively. The patients were classified according to the CPR response into a successful group (n = 46) and a failed group (n = 50).ResultsThe MMP-9 levels were detected to be 56.9 ± 4.3, 69.5 ± 7.4, and 92.7 ± 10.1 ng/mL in the control group, the successful CPR group (acute responders), and the failed CPR group, respectively (P < .001 for the 2 comparisons). The MMP-9 level on admission, presence … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
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| Web of Science | 9 |
| Google Scholar | 16 |