Schiff bases based on thio/carbohydrazide: Synthesis, spectroscopic characterization, DFT, antimicrobial, DNA interactions and cytotoxicity studies
Yazarlar (5)
Prof. Dr. Muhammet Serdar ÇAVUŞ Kastamonu Üniversitesi, Türkiye
Doç. Dr. Hasan Yakan Ondokuz Mayıs Üniversitesi, Türkiye
Dr. Öğr. Üyesi Ceren Başkan Amasya Üniversitesi, Türkiye
Prof. Dr. Halit MUĞLU Kastamonu Üniversitesi, Türkiye
Öğr. Gör. Aybüke Afra Babacan Amasya Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Molecular Structure (Q2) | ||
| Dergi ISSN | 0022-2860 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 05-2024 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-05-2024 |
| Cilt / Sayı / Sayfa | 1304 / 1 / 137655–0 | DOI | 10.1016/j.molstruc.2024.137655 |
| Makale Linki | http://dx.doi.org/10.1016/j.molstruc.2024.137655 | ||
| UAK Araştırma Alanları |
Atom, Molekül ve Lazer Fiziği
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| Özet |
| New Schiff bases (1–8) have been prepared from numerous aldehydes and thio/carbohydrazide. The chemical structures of these compounds were characterized using IR, 1H NMR, 13C NMR spectroscopic methods, and elemental analysis. Electronic and spectroscopic properties of the compounds were determined by DFT calculations performed at the B3LYP/6–311++G(2d,2p) level of theory and were analyzed comparatively with experimental findings. The relationship between some global reactivity parameters and the nucleophilic-electrophilic attack abilities of the compounds and their antimicrobial and cytotoxic activities was also investigated. The antimicrobial effects of the synthesized compounds on microorganisms were screened using disc diffusion methods. According to the disc diffusion results, compound 8 in particular exhibits a high antibacterial potential against Bacillus cereus (15.66 ± 0.57 mm … |
| Anahtar Kelimeler |
| Antimicrobial activity | Cytotoxicity studies | DFT | DNA interactions | Schiff bases | Structure characterization |
Science Direct
Schiff bases based on thio/carbohydrazide: Synthesis, spectroscopic characterization, DFT, antimicrobial, DNA interactions and cytotoxicity studies
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 14 |
| Scopus | 13 |
| Google Scholar | 15 |