Yazarlar |
Nuri Bakan
Atatürk Üniversitesi, Türkiye |
Ebubekir Bakan
Atatürk Üniversitesi, Türkiye |
Orhan Değer
Karadeniz Teknik Üniversitesi, Türkiye |
Mecit Süerdem
Selçuk Üniversitesi, Türkiye |
Prof. Dr. Yaşar Nuri ŞAHİN
Kastamonu Üniversitesi, Türkiye |
Hikmet Koçak
Atatürk Üniversitesi, Türkiye |
Özet |
Angiotensin-converting enzyme activity and its kinetic parameters were determined in both serum and lung tissue samples obtained from 17 patients with lung cancer and 21 control subjects, regardless of ethical base. The specific activities for cancerous and normal lung tissues were 67.2 +/- 27.3 (mean +/- SD) U/g protein and 28.5 +/- 5.4 U/g protein, respectively (P less than 0.001). Serum enzyme activity, on the other hand, was found to be higher in controls (198 +/- 42 U/L) than in patients (237 +/- 68 U/L) (P less than 0.01). The effects of chloride and zinc ions, pH and temperature on the enzyme activity were investigated as kinetic parameters in both serum and tissue samples. |
Anahtar Kelimeler |
Makale Türü | Özgün Makale |
Makale Alt Türü | Uluslararası alan indekslerindeki dergilerde yayımlanan tam makale |
Dergi Adı | Acta Med Hung. |
Dergi ISSN | 0236-5286 |
Makale Dili | İngilizce |
Basım Tarihi | 01-1988 |
Cilt No | 46 |
Sayı | 2 |
Sayfalar | 197 / 205 |