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Kinetic parameters of serum and lung tissue angiotensin-converting enzyme in patients with lung cancer     
Yazarlar
Nuri Bakan
Atatürk Üniversitesi, Türkiye
Ebubekir Bakan
Atatürk Üniversitesi, Türkiye
Orhan Değer
Karadeniz Teknik Üniversitesi, Türkiye
Mecit Süerdem
Selçuk Üniversitesi, Türkiye
Prof. Dr. Yaşar Nuri ŞAHİN Prof. Dr. Yaşar Nuri ŞAHİN
Kastamonu Üniversitesi, Türkiye
Hikmet Koçak
Atatürk Üniversitesi, Türkiye
Özet
Angiotensin-converting enzyme activity and its kinetic parameters were determined in both serum and lung tissue samples obtained from 17 patients with lung cancer and 21 control subjects, regardless of ethical base. The specific activities for cancerous and normal lung tissues were 67.2 +/- 27.3 (mean +/- SD) U/g protein and 28.5 +/- 5.4 U/g protein, respectively (P less than 0.001). Serum enzyme activity, on the other hand, was found to be higher in controls (198 +/- 42 U/L) than in patients (237 +/- 68 U/L) (P less than 0.01). The effects of chloride and zinc ions, pH and temperature on the enzyme activity were investigated as kinetic parameters in both serum and tissue samples.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü Uluslararası alan indekslerindeki dergilerde yayımlanan tam makale
Dergi Adı Acta Med Hung.
Dergi ISSN 0236-5286
Makale Dili İngilizce
Basım Tarihi 01-1988
Cilt No 46
Sayı 2
Sayfalar 197 / 205
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
SCOPUS 1

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