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Systemic immune inflammation index in patients with recurrent aphthous stomatitis     
Yazarlar
Dr. Öğr. Üyesi Fatma ATALAY
Kastamonu Üniversitesi, Türkiye
Ayhan Kars
Türkiye
Kübra Topal
Türkiye
Zeynep Yavuz
Türkiye
Özet
Objectives: Recurrent Aphthous Stomatitis (RAS) a chronic idiopathic oral mucosal disease. But yet the etiology and pathogenesis of RAS are not exactly known, it is thought that inflammation play an important role in the pathogenesis. The aim of this study is to demonstrate the role of systemic inflammation among the possible etiological factors of RAS and to find the possible diagnostic correlation between Systemic Immune Inflammation Index (SII). Methods: Patients who were consulted the otolaryngology outpatient clinic and diagnosed with RAS between 2019–2021 were retrospectively analyzed. Neutrophil/Lymphocyte Ratio (NLR), Platelet/Lymphocyte Ratio (PLR) and SII values were calculated based on the results of complete blood count. Demographic and hematological parameters between control and RAS groups were compared. The statistical significance level was considered as <0.05. Results: There was no statistically significant difference between the control and RAS groups in terms of sex and age distributions (p = 0.566 and p = 0.173, respectively). SII, NLR and PLR values were significantly higher in the RAS group compared to the controls (p < 0.001, p < 0.001 and p = 0.001, respectively). A very strong correlation between SII and NLR, moderately strong correlation between SII and PLR and moderate correlation between NLR and PLR values were detected (respectively ρ: 0.813, 0.719, 0.532; p-values <0.001). Conclusion: SII, NLR and PLR has significantly higher levels in the RAS group compared to the control group, that it supports the role of systemic inflammation in the etiopathogenesis of RAS. In addition, the results show that SII is a valuable marker for inflammation. Level of evidence: 4.
Anahtar Kelimeler
Hematinic deficiencies | Inflammatory marker | Recurrent aphthous stomatitis | Systemic immune inflammation index | Systemic inflammation
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY
Dergi ISSN 1808-8694
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q2
Makale Dili İngilizce
Basım Tarihi 07-2022
Cilt No 88
Sayı 4
Sayfalar 621 / 624
Doi Numarası 10.1016/j.bjorl.2022.02.007
Makale Linki http://dx.doi.org/10.1016/j.bjorl.2022.02.007
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 8
SCOPUS 8
Systemic immune inflammation index in patients with recurrent aphthous stomatitis

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