| Yazarlar |
Uğur Önal
Türkiye |
|
Muhammet Gülhan
Türkiye |
|
Neşe Demirci
|
|
Ahmet Özden
Türkiye |
Dr. Öğr. Üyesi Nazlı EROL
Türkiye |
|
Sema Işık
Türkiye |
Doç. Dr. Sedat GÜLTEN
Kastamonu Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Fatma ATALAY
Kastamonu Üniversitesi, Türkiye |
|
Nilay Çöplü
Türkiye |
| Özet |
| In this study it was aimed to evaluate the prognostic factors for the geriatric patients with confirmed COVID-19 in a tertiary-care hospital at Kastamonu region of Turkey. Patients (≥65-year-old) who had PCR positivity for COVID-19 between March 2020 and April 2020 in our center were recorded retrospectively. A p value less than 0.05 was considered significant. Ethical committee approval was given from the Bolu University with decision number 2020/176. There were a total of 100 patients (44% female). In-hospital mortality was recorded as 7%. In univariate analysis for 1 month mortality, diabetes mellitus (p = 0.038), leucocyte count (p = 0.005), neutrophile count (p = 0.02), neutrophile-to-lymphocyte ratio (NLR) (p < 0.001), thrombocyte-to-lymphocyte ratio (TLR) (p = 0.001), C-reactive protein (CRP) (p = 0.002), lactate dehydrogenase (LDH) (p = 0.001), sequential organ failure assessment (SOFA) score (p = 0.001) and qSOFA score (p = 0.002) were found as independent risk factors. On admission, one point increase of NLR (p = 0.014, odds ratio (OR) = 1.371, 95% CI = 1.067-1.761) and one point increase of LDH (p = 0.047, OR = 1.011, 95% CI = 1.001-1.023) were associated with mortality on day 30 according to logistic regression analysis. The cut-off values were found as > 7.8 for NLR (83.33% sensitivity, 97.7% specificity) and > 300 U/L for LDH (100% sensitivity, 79.31% specificity) regarding the prediction of 30-day mortality. In order to improve clinical management and identify the geriatric patients with COVID-19 who have high risk for mortality, NLR and LDH levels on admission might be useful prognostic tools. |
| Anahtar Kelimeler |
| Covid-19 | Geriatric patients | Neutrophile-to-lymphocyte ratio, lactate dehydrogenase | Prognostic factors |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | BMC GERIATRICS |
| Dergi ISSN | 1471-2318 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 04-2022 |
| Cilt No | 22 |
| Sayı | 1 |
| Sayfalar | 1 / 6 |
| Doi Numarası | 10.1186/s12877-022-03059-7 |
| Makale Linki | http://dx.doi.org/10.1186/s12877-022-03059-7 |
| Atıf Sayıları | |
| WoS | 7 |
| SCOPUS | 5 |
