| Yazarlar |
Derya Güroy
Türkiye |
|
Betül Güroy
Türkiye |
Doç. Dr. Soner BİLEN
Türkiye |
Doç. Dr. Ertuğrul TERZİ
Türkiye |
Arş. Gör. Dr. Osman Nezih KENANOĞLU
Türkiye |
|
Maria Garcia Suarez
|
|
Danièle Marzin
|
|
Serhan Mantoğlu
Türkiye |
|
Onur Karadal
Türkiye |
|
İzzet Şahin
Türkiye |
|
Halit Kuşku
Türkiye |
| Özet |
| The present study evaluated the effects of a dietary mix of marine sulphated polysaccharides, named Algimun® (AL), supplementation to gilthead seabream (Sparus aurata) juveniles in terms of growth performance, immune responses, and resistance against Photobacterium damselae subsp. piscicida. A total of 240 fish (initial mean weight of 6.00 ± 0.03 g) was randomly separated into 12 tanks (400 L, 20 fish per tank) distributed in four replicates. Fish were fed three experimental diets: a basal diet (Control), and a basal diet with two inclusion rates of Algimun® as 3 g/kg (AL0.3) and 5 g/kg (AL0.5) for 30 days before bacterial infection with P. damselae subsp. piscicida. After a 30-day feeding-period, growth performance was significantly improved in AL0.3 and AL0.5 groups compared to the control group (P < 0.05). AL0.3 and AL0.5 groups showed significantly higher lysozyme activity and myeloperoxidase activity when compared to the control group (P < 0.05). The gene expression of immune mediators (IL-1β, IL-6, IL-10, IL-18, TNF-α and COX-2) was significantly upregulated in the intestine, spleen and head kidney in AL0.3 and AL0.5 groups when compared to the control group (P < 0.05). Eight days post-challenge, the survival rate against P. damselae subsp. piscicida was numerically higher in fish within AL0.3 and AL0.5 groups compared to control (+20%). The study findings suggest that marine sulphated polysaccharides (Algimun®) could be used as an immunomodulator in gilthead seabream to support animal's health and boost resistance in case of disease outbreak. |
| Anahtar Kelimeler |
| Immunomodulation | Marine fish | Marine sulphate polysaccharide | Nutrition | Seaweed |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Fish & shellfish immunology |
| Dergi ISSN | 1050-4648 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q1 |
| Makale Dili | İngilizce |
| Basım Tarihi | 08-2022 |
| Cilt No | 127 |
| Sayı | 1 |
| Sayfalar | 1139 / 1147 |
| Doi Numarası | 10.1016/j.fsi.2022.07.054 |
| Makale Linki | https://www.sciencedirect.com/science/article/pii/S1050464822004430 |
| Atıf Sayıları | |
| SCOPUS | 3 |
