Inflammatory immune response by lipopolysaccharide responsive nucleotide binding oligomerization domain NOD like receptors in the Japanese pufferfish Takifugu rubripes
Yazarlar (5)
Gouranga Biswas
University Of Miyazaki, Japonya
University Of Miyazaki, Japonya
Doç. Dr. Soner BİLEN Kastamonu Üniversitesi, Türkiye
Tomoya Kono
University Of Miyazaki, Japonya
University Of Miyazaki, Japonya
Masahiro Sakai
University Of Miyazaki, Japonya
University Of Miyazaki, Japonya
Jun İchi Hikima
University Of Miyazaki, Japonya
University Of Miyazaki, Japonya
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Developmental and Comparative Immunology (Q1) | ||
| Dergi ISSN | 0145-305X Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2016 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-02-2016 |
| Cilt / Sayı / Sayfa | 55 / 1 / 21–31 | DOI | 10.1016/j.dci.2015.10.008 |
| Makale Linki | https://www.sciencedirect.com/science/article/pii/S0145305X15300525 | ||
| UAK Araştırma Alanları |
Su Ürünleri Yetiştiriciliği
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| Özet |
| Some of NOD-like receptors (NLRs), the cytosolic pattern recognition receptors form a multi-protein complex, inflammasome consisting of one or more NLRs, the adaptor protein ASC and inflammatory caspase to generate mature inflammatory cytokines, interleukin (IL)-1β and IL-18. However, inflammasome-mediated inflammatory cascade involving any NLR member is unknown in a lower vertebrate like fish. Also, inflammatory cytokine induction pathway in response to a specific ligand, namely bacterial lipopolysaccharide (LPS) has not yet been clarified. Therefore, 13 predicted NLR sequences of the Japanese pufferfish, Fugu (Takifugu rubripes) were retrieved in silico and categorized as NLR-C1∼13. Expression analysis of these genes in Fugu head kidney (HK) cells stimulated with a heat-killed Lactobacillus paracasei spp. paracasei (Lpp), LPS, nigericin and a combination of nigericin + LPS showed consistent … |
| Anahtar Kelimeler |
| Inflammasome | Inflammatory cytokines | Intracellular PRRs | Japanese pufferfish | LPS recognition | NLR |
Science Direct
Inflammatory immune response by lipopolysaccharide responsive nucleotide binding oligomerization domain NOD like receptors in the Japanese pufferfish Takifugu rubripes
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| Atıf Sayıları | |
| Scopus | 37 |
| Google Scholar | 44 |