Immune responses to methanolic extract of black cumin ( Nigella sativa ) in rainbow trout ( Oncorhynchus mykiss )
 
Yazarlar (4)
Prof. Dr. Yasemin ÇELİK ALTUNOĞLU Kastamonu Üniversitesi, Türkiye
Doç. Dr. Soner BİLEN Kastamonu Üniversitesi, Türkiye
Dr. Öğr. Üyesi Ferhat ULU Kastamonu Üniversitesi, Türkiye
Gouranga Biswas
Icar - Central Institute Of Brackishwater Aquaculture, Chennai, Hindistan
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Fish and Shellfish Immunology (Q1)
Dergi ISSN 1050-4648 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 08-2017
Kabul Tarihi Yayınlanma Tarihi 01-08-2017
Cilt / Sayı / Sayfa 67 / 1 / 103–109 DOI 10.1016/j.fsi.2017.06.002
Makale Linki https://www.sciencedirect.com/science/article/pii/S1050464817303236?casa_token=HmGJOtKVNWgAAAAA:luUnrkSWwyoVQ0WU6JuwfEaxQ5gFPFA0qGiGNLeXSNwvmRe30fnIPEm7uhA132rF0YyEn4cMFko
UAK Araştırma Alanları
Su Ürünleri Yetiştiriciliği
Özet
The immune stimulating effects of the methanolic extract of black cumin (Nigella sativa) in rainbow trout (Oncorhynchus mykiss) was evaluated. Variable concentrations of black cumin methanolic extract [0 (Control), 0.1 and 0.5 g kg−1 of feed] were individually added to the basal diet and rainbow trout was fed for 30 days to assess the innate immune responses and growth performance. Feed conversion ratio significantly decreased in the group fed with 0.5 g kg−1 black cumin extract. Respiratory burst activity was observed to be the highest in the 0.5 g kg−1 black cumin extract fed group. Lysozyme and myeloperoxidase activities were significantly increased in fish of experimental groups compared to control (P < 0.05). TGF-β gene expression increased in black cumin 0.5 g kg−1 treated group. IL-1β and TGF-β gene expressions decreased in black cumin 0.1 g kg−1 administered group. Expression of IL-12 gene …
Anahtar Kelimeler
Black cumin methanolic extract | Cytokine response | Growth promotion | Immunostimulant | Rainbow trout