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Effect of lemon balm (Melissa officinalis) extract on growth performance, digestive and antioxidant enzyme activities, and immune responses in rainbow trout (Oncorhynchus mykiss)      
Yazarlar
Doç. Dr. Soner BİLEN Doç. Dr. Soner BİLEN
Kastamonu Üniversitesi, Türkiye
Tarek Abdalsalam Salem Altıef
Dr. Öğr. Üyesi Keriman YÜRÜTEN ÖZDEMİR Dr. Öğr. Üyesi Keriman YÜRÜTEN ÖZDEMİR
Türkiye
Mohamed Omar Abdalla Salem
Doç. Dr. Ertuğrul TERZİ Doç. Dr. Ertuğrul TERZİ
Türkiye
Dr. Öğr. Üyesi Kerim GÜNEY Dr. Öğr. Üyesi Kerim GÜNEY
Türkiye
Özet
This study was conducted to determine the effects of dietary supplementation of lemon balm (Melissa officinalis) aqueous methanolic extract on growth performance, blood parameters, digestive and antioxidant enzyme activities, and non-specific immune responses in rainbow trout (Oncorhynchus mykiss). Fish with an average weight of 23.03 ± 0.07 g were fed a diet supplemented with an aqueous methanolic extract of lemon balm at a dose of 0 (control), 0.1 (LB0.1), 0.5 (LB0.5), and 1 g kg−1 (LB1) for 75 days. The final weight, weight gain, and specific growth rate were observed to be significantly increased in LB0.5 and LB1 groups compared with that of the control. No differences were observed in feed conversion ratio values. WBC increased at the 45th day of the study in LB0.1 group. No differences were determined in RBC (P > 0.05). At the end of the study, lipase increased significantly in all experimental groups compared with the control. Pepsin was also elevated in LB0.5 and LB1 groups compared with the control. Increased trypsin was determined in LB1 group (P < 0.05). SOD activity increased at the end of the study in LB1 group (P < 0.05). CAT values had no differences compared with control. GR activity increased in all experimental groups compared with control. GPx improved in LB0.5 and LB1 groups significantly (P < 0.05). Lipid peroxidation was decreased in LB1 group compared with that of control, but this decrease was not significant (P < 0.05). Oxidative radical production and lysozyme activity significantly increased in LB1 group (P < 0.05). The highest MPO was determined in control group (P < 0.05). Current results suggest that lemon balm extract stimulates growth promoting antioxidant and immune responses in rainbow trout.
Anahtar Kelimeler
Antioxidant | Digestive enzyme | Growth | Hematology | Immune responses | Lemon balm | Melissa officinalis
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı FISH PHYSIOLOGY AND BIOCHEMISTRY
Dergi ISSN 0920-1742
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q2
Makale Dili İngilizce
Basım Tarihi 01-2020
Cilt No 46
Sayı 1
Sayfalar 471 / 481
Doi Numarası 10.1007/s10695-019-00737-z
Makale Linki http://link.springer.com/10.1007/s10695-019-00737-z