Beneficial effects of curcumin in the diabetic rat ovary: a stereological and biochemical study
Yazarlar (2)
Doç. Dr. Kıymet Kübra TÜFEKCİ Kastamonu Üniversitesi, Türkiye
Öğr. Gör. Süleyman Kaplan Ondokuz Mayis University, Medical School, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Histochemistry and Cell Biology (Q1) | ||
| Dergi ISSN | 0948-6143 Dergi Bilgileri (2023) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 05-2023 |
| Cilt / Sayı / Sayfa | 159 / 5 / 401–430 | DOI | 10.1007/s00418-022-02171-4 |
| Makale Linki | http://dx.doi.org/10.1007/s00418-022-02171-4 | ||
| UAK Araştırma Alanları |
Histoloji ve Embriyoloji
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| Özet |
| This study aimed to investigate the effects of curcumin treatment on ovaries at different periods of the diabetes disease. Fifty-six female Wistar albino rats (250–300 g) aged 12 weeks were divided into seven groups. No treatment was applied to the control group. The sham group was given 5 mL/kg of corn oil, and the curcumin group 30 mg/kg curcumin. In the diabetes mellitus (DM) groups, diabetes was induced by a single intraperitoneal dose of 50 mg/kg streptozotocin (STZ). The DM-treated groups received 30 mg/kg curcumin after either 7 days (DC1 group) or 21 days (DC2 group), or simultaneously with STZ injection (DC3 group). Number of follicles in the ovaries was estimated using stereological method. Follicle-stimulating hormone (FSH), luteinizing hormone (LH), and superoxide dismutase (SOD) levels and catalase (CAT) activity were measured in serum specimens. We found that follicle number and … |
| Anahtar Kelimeler |
| Antioxidant | Curcumin | Diabetes | Follicle number | Oxidative stress | Stereology |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 12 |
| Scopus | 12 |
| Google Scholar | 15 |