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An investigation of the endoplasmic reticulum stress in obesity exposure in the prenatal period    
Yazarlar
Doç. Dr. Kıymet Kübra TÜFEKCİ
Kastamonu Üniversitesi, Türkiye
Doç. Dr. Musa TATAR
Türkiye
Doç. Dr. Funda TERZİ
Türkiye
Elfide Gizem Bakırhan
Türkiye
Özet
Exposure to maternal obesity has been shown to make offspring more prone to cognitive and metabolic disorders later in life. Although the underlying mechanisms are unclear, the role of endoplasmic reticulum (ER) stress in the fetal programming process is remarkable. ER stress can be activated by many chronic diseases, including obesity and diabetes. Therefore, our study aimed to investigate the role of ER stress caused by maternal diet-induced obesity in the offspring hippocampus. We also evaluated the protective effect of N-acetylcysteine (NAC) against ER stress.
Anahtar Kelimeler
Endoplasmic reticulum stress,Brain,Hippocampus,Memory,N-acetylcysteine
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Elsevier BV
Dergi ISSN 0891-0618
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q3
Makale Dili Türkçe
Basım Tarihi 12-2023
Cilt No 134
Doi Numarası 10.1016/j.jchemneu.2023.102348
Makale Linki http://dx.doi.org/10.1016/j.jchemneu.2023.102348
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
An investigation of the endoplasmic reticulum stress in obesity exposure in the prenatal period

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