Yazarlar |
Doç. Dr. Kıymet Kübra TÜFEKCİ
Kastamonu Üniversitesi, Türkiye |
Doç. Dr. Musa TATAR
Türkiye |
Doç. Dr. Funda TERZİ
Türkiye |
Elfide Gizem Bakırhan
Türkiye |
Özet |
Exposure to maternal obesity has been shown to make offspring more prone to cognitive and metabolic disorders later in life. Although the underlying mechanisms are unclear, the role of endoplasmic reticulum (ER) stress in the fetal programming process is remarkable. ER stress can be activated by many chronic diseases, including obesity and diabetes. Therefore, our study aimed to investigate the role of ER stress caused by maternal diet-induced obesity in the offspring hippocampus. We also evaluated the protective effect of N-acetylcysteine (NAC) against ER stress. |
Anahtar Kelimeler |
Endoplasmic reticulum stress,Brain,Hippocampus,Memory,N-acetylcysteine |
Makale Türü | Özgün Makale |
Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
Dergi Adı | Elsevier BV |
Dergi ISSN | 0891-0618 |
Dergi Tarandığı Indeksler | SCI-Expanded |
Dergi Grubu | Q3 |
Makale Dili | Türkçe |
Basım Tarihi | 12-2023 |
Cilt No | 134 |
Doi Numarası | 10.1016/j.jchemneu.2023.102348 |
Makale Linki | http://dx.doi.org/10.1016/j.jchemneu.2023.102348 |