The protective effect of curcumin on the diabetic rat kidney: A stereological, electron microscopic and immunohistochemical study
 
Yazarlar (4)
Mahmut Ulubay University Of Health Sciences, Türkiye
Işınsu Alkan Ondokuz Mayis Üniversitesi, Türkiye
Doç. Dr. Kıymet Kübra TÜFEKCİ Kastamonu Üniversitesi, Türkiye
Süleyman Kaplan Ondokuz Mayis Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Acta Histochemica (Q4)
Dergi ISSN 0065-1281 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 02-2020
Cilt / Sayı / Sayfa 122 / 2 / 151486–0 DOI 10.1016/j.acthis.2019.151486
Makale Linki http://dx.doi.org/10.1016/j.acthis.2019.151486
UAK Araştırma Alanları
Histoloji ve Embriyoloji
Özet
The prevalence of diabetes in the world is increasing rapidly. Kidney diseases are among the most common medical disorders. The aim of this study was to investigate the effect of curcumin on the diabetic kidney. Thirty-five female Wistar albino rats were divided into seven groups. No procedure was performed on the Cont group. The Sham group received corn oil via gavage for 14 days. The curcumin (Curc) group received 30-mg/kg curcumin for 14 days, while the diabetes mellitus (DM) group received 50-mg/kg streptozotocin (STZ) in a single dose intraperitoneally. The DM + curcumin 1 (DC1) group received 30 mg/kg curcumin for 14 days, seven days after the application of STZ, while the DM + curcumin 2 (DC2) received 30 mg/kg curcumin for 14 days, 21 days after the application of STZ, and the DM + curcumin 3 (DC3) group received single-dose STZ at the same time as the application of 30 mg/kg …
Anahtar Kelimeler
Curcumin | Diabetes mellitus | Diabetic nephropathy | Histopathology | Stereology