Prenatal exposure to low-dose diclofenac sodium does not affect total neuron numbers in spinal segment T13 in rats
Yazarlar (8)
Murat Çetin Ragbetli Van Yüzüncü Yıl Üniversitesi, Türkiye
Mikail Kara Van Yüzüncü Yıl Üniversitesi, Türkiye
Neşe Çölçimen Van Yüzüncü Yıl Üniversitesi, Türkiye
Necat Koyun Van Yüzüncü Yıl Üniversitesi, Türkiye
Gamze Çakmak Van Yüzüncü Yıl Üniversitesi, Türkiye
Veysel Akyol Van Yüzüncü Yıl Üniversitesi, Türkiye
Omur Gulsum Deniz Ondokuz Mayis Üniversitesi, Türkiye
Doç. Dr. Kıymet Kübra TÜFEKCİ Ondokuz Mayis Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Chemical Neuroanatomy (Q3) | ||
| Dergi ISSN | 0891-0618 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2018 |
| Cilt / Sayı / Sayfa | 87 / 1 / 49–53 | DOI | 10.1016/j.jchemneu.2017.05.001 |
| Makale Linki | http://dx.doi.org/10.1016/j.jchemneu.2017.05.001 | ||
| UAK Araştırma Alanları |
Histoloji ve Embriyoloji
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| Özet |
| The main purpose of the present study was to investigate the effects of diclofenac sodium (DS) on the total number of neurons in segment T13 of the spinal cord of offspring of pregnant rats using stereological methods. Eighteen adult female Wistar albino rats weighing 150–200 g were used. Pregnant female rats were divided into three groups; a control group, a sham group and a DS (1 mg/kg, intramuscular) exposed group. The DS and sham groups received injection from the 5th day of gestation to the 19th. Twenty eight days after birth, the offspring rats were perfused with 4% buffered formalin. T13, which is one of transverse spinal cord segments, were isolated and processed for routine paraffin histology. 5 μm sections were obtained using a rotary microtome according to systematic random sampling strategies. Every 40th section was taken and sections were stained with modified Giemsa. All types of motor … |
| Anahtar Kelimeler |
| Diclofenac sodium | Motoneurons | Prenatal | Rat | Spinal segment T13 | Stereology |
Science Direct
Prenatal exposure to low-dose diclofenac sodium does not affect total neuron numbers in spinal segment T13 in rats
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 1 |
| Scopus | 3 |
| Google Scholar | 2 |