Garcinia kola aqueous suspension prevents cerebellar neurodegeneration in long-term diabetic rat – a type 1 diabetes mellitus model
Yazarlar (12)
Mohammed Farahna Qassim University, Suudi Arabistan
Paul F. Seke Etet Qassim University, Suudi Arabistan
Sayed Y. Osman Qassim University, Suudi Arabistan
Doç. Dr. Kıymet Kübra TÜFEKCİ Ondokuz Mayis Üniversitesi, Türkiye
Naheed Amir College Of Medicine And Health Sciences United Arab Emirates University, Birleşik Arap Emirlikleri
Lorella Vecchio Qassim University, Suudi Arabistan
Isınsu Aydin Ondokuz Mayis Üniversitesi, Türkiye
Yousef H. Aldebasi Qassim University, Suudi Arabistan
Azimullah Sheikh College Of Medicine And Health Sciences United Arab Emirates University, Birleşik Arap Emirlikleri
John C. Chijuka Qassim University, Suudi Arabistan
Süleyman Kaplan Ondokuz Mayis Üniversitesi, Türkiye
Abdu Adem College Of Medicine And Health Sciences United Arab Emirates University, Birleşik Arap Emirlikleri
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Ethnopharmacology (Q1) | ||
| Dergi ISSN | 0378-8741 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2017 |
| Cilt / Sayı / Sayfa | 195 / 1 / 159–165 | DOI | 10.1016/j.jep.2016.11.001 |
| Makale Linki | http://dx.doi.org/10.1016/j.jep.2016.11.001 | ||
| UAK Araştırma Alanları |
Histoloji ve Embriyoloji
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| Özet |
| Ethnopharmacological relevanceThe development of compounds able to improve metabolic syndrome and mitigate complications caused by inappropriate glycemic control in type 1 diabetes mellitus is challenging. The medicinal plant with established hypoglycemic properties Garcinia kola Heckel might have the potential to mitigate diabetes mellitus metabolic syndrome and complications.Aim of the studyWe have investigated the neuroprotective properties of a suspension of G. kola seeds in long-term type 1 diabetes mellitus rat model.Materials and methodsWistar rats, made diabetic by single injection of streptozotocin were monitored for 8 months. Then, they were administered with distilled water or G. kola oral aqueous suspension daily for 30 days. Body weight and glycemia were determined before and after treatment. After sacrifice, cerebella were dissected out and processed for stereological quantification of … |
| Anahtar Kelimeler |
| Ataxia | Garcinia kola | Medicinal plant | Neuroprotection | Purkinje cell | Type 1 diabetes mellitus |
Science Direct
Garcinia kola aqueous suspension prevents cerebellar neurodegeneration in long-term diabetic rat – a type 1 diabetes mellitus model
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 14 |
| Scopus | 16 |
| Google Scholar | 22 |