Effects of diclofenac sodium on the hippocampus of rats with acute subdural hematoma: histological, stereological, and molecular approach
Yazarlar (8)
Aysin Pinar Türkmen Ondokuz Mayis Üniversitesi, Türkiye
Suleyman Kaplan Ondokuz Mayis Üniversitesi, Türkiye
Abdurrahman Aksoy Ondokuz Mayis Üniversitesi, Türkiye
Berrin Zuhal Altunkaynak Ondokuz Mayis Üniversitesi, Türkiye
Doç. Dr. Kıymet Kübra TÜFEKCİ Ondokuz Mayis Üniversitesi, Türkiye
Ebru Elibol Ondokuz Mayis Üniversitesi, Türkiye
Cengiz Çokluk Ondokuz Mayis Üniversitesi, Türkiye
Mehmet Emin Onger Ondokuz Mayis Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Folia Neuropathologica (Q3) | ||
| Dergi ISSN | 1641-4640 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2016 |
| Cilt / Sayı / Sayfa | 54 / 2 / 167–179 | DOI | 10.5114/fn.2016.60808 |
| Makale Linki | http://dx.doi.org/10.5114/fn.2016.60808 | ||
| UAK Araştırma Alanları |
Histoloji ve Embriyoloji
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| Özet |
| This study was aimed at evaluating the potential effects of acute subdural hematoma (ASDH) and diclofenac sodium (DS) therapy following ASDH on the rat hippocampus.Twenty-four male Sprague Dawley rats were used and divided into four groups. 0.1 ml of non-heparinized autologous blood from the tail vein of the animals in the non-treatment group (NTG) and treatment group (TG) was injected into the subdural space. The TG received intramuscular diclofenac sodium at a 15 mg/kg dose daily from the postoperative second hour to the seventh day after the operation. The control group (CG) and sham group (SG) were used for control and sham operations, respectively. On the postoperative eighth day, all animals were sacrificed, and the hippocampi of all animals were stereologically and histologically evaluated. Also blood samples of the animals were biochemically analyzed. |
| Anahtar Kelimeler |
| Acute subdural hematoma | Diclofenac sodium | Hippocampus | Rat | Stereology |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 6 |
| Scopus | 10 |
| Google Scholar | 6 |