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Effects of mobile phone exposure on metabolomics in the male and female reproductive systems        
Yazarlar
Gamze Altun
Ondokuz Mayıs Üniversitesi, Türkiye
Ömür Gülsüm Deniz
Türkiye
Doç. Dr. Kıymet Kübra TÜFEKCİ
Ondokuz Mayıs Üniversitesi, Türkiye
Devra Davis
Süleyman Kaplan
Türkiye
Özet
With current advances in technology, a number of epidemiological and experimental studies have reported a broad range of adverse effects of electromagnetic fields (EMF) on human health. Multiple cellular mechanisms have been proposed as direct causes or contributors to these biological effects. EMF-induced alterations in cellular levels can activate voltage-gated calcium channels and lead to the formation of free radicals, protein misfolding and DNA damage. Because rapidly dividing germ cells go through meiosis and mitosis, they are more sensitive to EMF in contrast to other slower-growing cell types. In this review, possible mechanistic pathways of the effects of EMF exposure on fertilization, oogenesis and spermatogenesis are discussed. In addition, the present review also evaluates metabolomic effects of GSM-modulated EMFs on the male and female reproductive systems in recent human and animal studies. In this context, experimental and epidemiological studies which examine the impact of mobile phone radiation on the processes of oogenesis and spermatogenesis are examined in line with current approaches.
Anahtar Kelimeler
Mobile phone exposure | Oogenesis | Oxidative stress | Spermatogenesis
Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü SCI, SSCI, AHCI, SCI-Exp dergilerinde yayımlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale
Dergi Adı ENVIRONMENTAL RESEARCH
Dergi ISSN 0013-9351
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 11-2018
Cilt No 167
Sayı 1
Sayfalar 700 / 707
Doi Numarası 10.1016/j.envres.2018.02.031
Makale Linki http://dx.doi.org/10.1016/j.envres.2018.02.031