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The effect of low-level laser therapy on rat unicortical femoral defect    
Yazarlar
Latif Emrah Yanmaz
Atatürk Üniversitesi, Türkiye
Uğur Ersöz
Atatürk Üniversitesi, Türkiye
Sıtkıcan Okur
Atatürk Üniversitesi, Türkiye
Betül Yıldırım
Türkiye
Selim Çomaklı
Atatürk Üniversitesi, Türkiye
Yavuz Selim Sağlam
Türkiye
Doç. Dr. Elif DOĞAN
Kastamonu Üniversitesi, Türkiye
Ömer Karataş
Ferda Turgut
Türkiye
Zafer Okumuş
Türkiye
Özet
The aim of this study was to determine the effectiveness of low-level laser therapy (LLLT) in the healing of experimentally created unicortical defect (UCD) of rat femurs. Twenty-four adult Wister rats were randomly divided into 2 groups: UCD and UCD+LLLT. The animals were subdivided into 3 groups (each group had 4 animals) and then they sacrificed at day 8, 15 and 22 for radiological, pathological and biochemical analysis. Bone healing was significantly different between the groups at day 15 and 22 (P < 0.05), while bone formation was significantly increased in the UCD+LLLT group at day 22 compared to the UCD group (P < 0.05). On histopathological examination, significant difference was found between the UCD and UCD+LLLT groups on the 22nd day (P < 0.05) while there was no difference on the 8th and 15th day. In the UCD group, the plasma Alkaline phosphatase activity decreased on the 15th and 22nd days, Calcium on the 15th day and Phosphorus on the 8th and 22nd days compared to the UCD+LLLT group. In addition, Glutathione levels, Plasma Catalase, Glutathione Peroxidase and Superoxide Dismutase activity significantly reduced in the UCD group compared with UCD+LLLT on the 8th, 15th and 22nd day (P < 0.05). In conclusion, LLLT applied at a dose of 904μm accelerates fracture healing in UCD of a rat's femur. However, this effect shows an increase after the 22nd day of LLLT application.
Anahtar Kelimeler
Bone,Defect,Femur,Healing,Rat
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Thai Journal of Veterinary Medicine
Dergi ISSN 0125-6491
Dergi Tarandığı Indeksler SSCI
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 01-2021
Doi Numarası 10.14456/tjvm.2021
Makale Linki https://www.semanticscholar.org/paper/The-effect-of-low-level-laser-therapy-on-rat-defect-Yanmaz-Ersoz/b6118fda3ba4f1d1302353ba9f77e71eb2271067
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 1
SCOPUS 1
The effect of low-level laser therapy on rat unicortical femoral defect

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