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Comparison of propofol ketamine and ketofol on intraocular pressure in New Zealand white rabbits    
Yazarlar
Doç. Dr. Elif DOĞAN
Atatürk Üniversitesi, Türkiye
Latif Emrah Yanmaz
Atatürk Üniversitesi, Türkiye
Şenocak Mümin Gökhan
Zafer Okumuş
Atatürk Üniversitesi, Türkiye
Özet
This study was aimed to compare the effects of intravenous administration of propofol, ketamine and ketofol on intraocular pressure after intravenous premedication with xylazine (0.6 mg/kg) in rabbits. Eight healthy New Zealand white rabbits were randomly received each one of three anaesthetic regimen seperately at 1-week intervals. The intraocular pressure was measured at baseline, 15 minutes after xylazine administration, and at 2, 5, 10, 20 and 25 minutes following induction. The mean of the left and right intraocular pressure was assumed as the animals intraocular pressure. There were no significant differences between groups at all time intervals except for 20 minutes following induction. The mean intraocular pressures at 20 minutes in propofol, ketamine and ketofol groups were 7.31 ± 1.88, 8.68 ± 1.41 and 8.31 ± 0.79 mm Hg, respectively. Intravenous ketamine (2 mg/ kg) and propofol (2 mg/kg) combination in New Zealand white rabbits is reduced the intraocular pressure compared to propofol and ketamine, alone. Ketofol may be an agent of choice for opthalmic procedures.
Anahtar Kelimeler
Intraocular pressure,propofol,ketamine,ketofol,New Zealand white rabbits,xylazine
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Revue de Médecine Vétérinaire
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 02-2016
Cilt No 167
Sayı 1
Sayfalar 18 / 21
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 4
SCOPUS 4

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