Effects of naringin on oxidative stress, inflammation, some reproductive parameters, and apoptosis in acrylamide-induced testis toxicity in rat.
Yazarlar (5)
Prof. Dr. Emin Şengül Atatürk Üniversitesi, Türkiye
Volkan Gelen Kafkas Üniversitesi, Veteriner Fakültesi, Türkiye
Prof. Dr. Serkan Yıldırım Atatürk Üniversitesi, Türkiye
Doç. Dr. İrfan ÇINAR Kastamonu Üniversitesi, Türkiye
Prof. Dr. Emrah Hicazi Aksu Kastamonu Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Environmental Toxicology (Q1) | ||
| Dergi ISSN | 1520-4081 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2023 |
| Cilt / Sayı / Sayfa | 38 / 4 / 798–808 | DOI | 10.1002/tox.23728 |
| Makale Linki | https://onlinelibrary.wiley.com/doi/full/10.1002/tox.23728 | ||
| Özet |
| Acrylamide (ACR) is used in many fields such as cosmetics, paper, and textile industries. It also occurs at very high temperatures in some foods. Gonadotoxic effects of ACR have been found in experimental animals. Many studies use flavonoids to prevent the reproductive side effects of ACR. Naringin (NA) is a flavonoid and it has been determined by studies that it has no toxic effect on tissues. In our study, we aimed to determine the protective effect of NA against the damage of ACR on testicular tissue and the reproductive system in rats. In our study, 50 Spraque Dawley male rats weighing 220‐250 grams were used. Control: Only intragastric saline was administered for 10 days. ACR: Animals received ACR (40 mg/kg, intraperitoneally) for 10 days. NA50+ACR: Animals were given NA for 10 days and each NA was one hour after the administration of ACR. NA100+ACR: Animals received NA for 10 days and one … |
| Anahtar Kelimeler |
| acrylamide | apoptosis | inflammation | naringin | oxidative stress | testicular toxicity |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 35 |
| Scopus | 40 |
| Google Scholar | 45 |