Dose-dependent effect of radiation on resorbable blast material titanium implants: an experimental study in rabbits
Yazarlar (6)
Gülnihal Emrem Doğan
Prof. Dr. Zekai Halici Ataturk University, Faculty Of Medicine, Türkiye
Emre Karakus
Dr. Öğr. Üyesi Burak Erdemci Ataturk University, Faculty Of Medicine, Türkiye
Akgün Alsaran Anadolu Üniversitesi, Türkiye
Doç. Dr. İrfan ÇINAR Ataturk University, Faculty Of Medicine, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Acta Odontologica Scandinavica (Q2) | ||
| Dergi ISSN | 0001-6357 Dergi Bilgileri (2018) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 10-2018 |
| Cilt / Sayı / Sayfa | 76 / 2 / 130–134 | DOI | 10.1080/00016357.2017.1392601 |
| Makale Linki | https://www.tandfonline.com/doi/full/10.1080/00016357.2017.1392601 | ||
| UAK Araştırma Alanları |
Tıbbi Farmakoloji
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| Özet |
| Background: Radiotherapy is a commonly used treatment modality in head and neck cancer; however, it also negatively affects healthy structures. Direct damage to oral soft and hard tissue frequently occurs with radiotherapy. In this study, we aimed to evaluate the effect of radiotherapy on bone surrounding titanium dental implants via biomechanical and molecular methods.Materials and methods: Fifty-four implants were inserted in the left tibiae of 18 adult male New Zealand rabbits (3 implants in each rabbit). After 4 weeks of the implant surgery, the left tibiae of 12 rabbits were subjected to a single dose of irradiation (15 Gy or 30 Gy). Four weeks after the irradiation, rabbits were sacrificed and removal torque test was done for the biomechanical evaluation. Bone morphogenetic protein-2 (Bmp-2) and fibroblast growth factor-2 (Fgf-2) expression analyses were performed with Real-time PCR. Statistical analysis … |
| Anahtar Kelimeler |
| dental | experimental study | implant | Radiation |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 3 |
| Scopus | 3 |
| Google Scholar | 7 |