| Yazarlar |
Erdinç Bozkurt
Kafkas Üniversitesi, Türkiye |
|
Ersin Muhafiz
Kafkas Üniversitesi, Türkiye |
|
Muhammed Yayla
Kafkas Üniversitesi, Türkiye |
Doç. Dr. İrfan ÇINAR
Kastamonu Üniversitesi, Türkiye |
| Özet |
| To detect the presence of urotensin-2 (U-II) in the aqueous humor and evaluate the relationship between aqueous humor level and systemic diseases and pupil size. The study included 88 patients who underwent cataract surgery. Those with a pupil diameter (PD) of up to 4 mm were considered to have small dilation, those with 4-7 mm of dilatation were considered to have moderate dilation, and those with a PD of more than 7 mm considered to have large dilation. Patients with HT (hypertension) were classified as group 1, those with DM (diabetes mellitus) as group 2, and those with HT+DM as group 3, and those without any systemic disease as group 4. The U-II levels in humor aqueous samples taken from anterior chamber were measured. When compared with the control group, it was observed that the level of U-II in the aqueous humor of the HT, DM, and DM+HT groups was significantly higher ( < 0.05). At the same time, when we compared the DM+HT group with the other groups, the level of U-II in the aqueous humor was significantly higher compared to the group with DM ( < 0.05). The U-II levels of the aqueous humor were higher in the patients with small pupils compared to the remaining groups ( < 0.005). U-II may play a role in small pupil pathophysiology. In addition, it was determined that patients with HT and/or diabetes had higher U-II levels in the aqueous humor than healthy individuals. |
| Anahtar Kelimeler |
| aqueous humor | diabetes mellitus | hypertension | pupil size | urotensin-II |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS |
| Dergi ISSN | 1080-7683 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q2 |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2021 |
| Cilt No | 37 |
| Sayı | 1 |
| Sayfalar | 45 / 51 |
| Doi Numarası | 10.1089/jop.2020.0086 |
| Makale Linki | http://dx.doi.org/10.1089/jop.2020.0086 |
| Atıf Sayıları | |
| WoS | 1 |
| Google Scholar | 1 |
