Evaluation of Endothelial Dysfunction in Bipolar Affective Disorders: Serum Endocan and Urotensin-II Levels
Yazarlar (5)
Elif Oral İzmir Katip Çelebi Üniversitesi, Türkiye
Prof. Dr. Zekai Halıcı Atatürk Üniversitesi, Türkiye
Doç. Dr. İrfan ÇINAR Kafkas Üniversitesi, Türkiye
Elıf Ozcan Erzurum Regional Education And Research Hospital, Türkiye
Zerrin Kutlu Atatürk Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
|
||
| Dergi Adı | Clinical Psychopharmacology and Neuroscience (Q3) | ||
| Dergi ISSN | 1738-1088 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 05-2019 |
| Cilt / Sayı / Sayfa | 17 / 2 / 211–221 | DOI | 10.9758/cpn.2019.17.2.211 |
| Makale Linki | http://www.cpn.or.kr/journal/view.html?doi=10.9758/cpn.2019.17.2.211 | ||
| Özet |
| Objective This study investigated changes in urotensin-II (U-II) and endocan levels which can be used as an early biological marker of endothelial injury in the episode and remission phases of bipolar affective disorder (BAD). Methods We compared endocan and U-II levels, which has been shown to be closely associated with neurotransmitter systems in addition to continuity of endothelial structure and inflammatory response, in patients with BAD in remission for at least one year (n=42) and in patients still in manic or depressive episodes (n=16) with healthy controls (n=30). Results Both endocan and U-II levels were significantly higher in the bipolar patients than in the controls. Endocan and U-II levels were also significantly correlated with one another (p=0.000, r=0.833). Both endocan (p=0.000) and U-II levels (p=0.000) were significantly higher in the bipolar attack group compared to the subjects in remission … |
| Anahtar Kelimeler |
| Bipolar disorder | Endocan | Endothelial injury | Urotensins |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 10 |
| Scopus | 11 |
| Google Scholar | 16 |