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Immature Granulocyte and Other Markers in Prediction of the Short-term and Long-term Prognosis of Patients with Acute Ischemic Stroke     
Yazarlar
Dr. Öğr. Üyesi İdris KOCATÜRK Dr. Öğr. Üyesi İdris KOCATÜRK
Türkiye
Doç. Dr. Sedat GÜLTEN Doç. Dr. Sedat GÜLTEN
Kastamonu Üniversitesi, Türkiye
Özet
Background & Objectives: To evaluate immature granulocytes, a new inflammatory biomarker, and other markers in short- and long-term prognosis in patients with acute ischemic stroke (AIS). Methods: Laboratory information system data from a tertiary hospital in Turkiye were used in this retrospective study. Of the 327 patients with the diagnosis of AIS, 275 recovered, and 52 died. It was determined that 31 of these 275 patients, who were followed up retrospectively, died within 12 months after discharge. Routinely measured immature granulocyte (IG), other hemogram parameters in the Sysmex XN 1000 (XN-1000-Hematology-Analyzer-Sysmex Corporation, Japan), and demographic data were statistically compared in both groups. We tried to estimate the short- and long-term mortality from the blood samples of these patients at their first admission to the hospital. Results: Of the patients included in the study, 150 (45.9%) were female, and 177 (54.1%) were male. National Institutes Of Health Stroke Scale (NIHSS) (AUC=960), length of stay (AUC=791), red blood cell distribution width – standard deviation (RDW-CV) (AUC=728), and IG (AUC=712) were the most effective parameters in predicting short-term mortality, while age (AUC=764) in predicting long-term mortality was the most effective parameters. Conclusion: IG, together with NIHSS and length of stay, shows moderate and high predictive properties in prognosticating short-term mortality but is ineffective in prognosticating long-term mortality. Age was found to be the most predictive marker for long-term mortality.
Anahtar Kelimeler
Acute ischemic stroke | immature granulocyte | inflammation | mortality | prognosis
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı NEUROLOGY ASIA
Dergi ISSN 1823-6138
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 12-2023
Cilt No 28
Sayı 4
Sayfalar 825 / 833
Doi Numarası 10.54029/2023dcd
Makale Linki http://dx.doi.org/10.54029/2023dcd