Antimicrobial Activity of a New Class of Phosphorylated and Modified Flavonoids
Yazarlar (7)
Francis J Osonga
Binghamton University State University Of New York, Amerika Birleşik Devletleri
Binghamton University State University Of New York, Amerika Birleşik Devletleri
Prof. Dr. Ali Akgul College Of Veterinary Medicine, Amerika Birleşik Devletleri
Roland Miller
Binghamton University State University Of New York, Amerika Birleşik Devletleri
Binghamton University State University Of New York, Amerika Birleşik Devletleri
Gaddi Eshun
Binghamton University State University Of New York, Amerika Birleşik Devletleri
Binghamton University State University Of New York, Amerika Birleşik Devletleri
Prof. Dr. İdris YAZGAN Kastamonu Üniversitesi, Türkiye
Ayfer Akgul
College Of Forest Resources, Amerika Birleşik Devletleri
College Of Forest Resources, Amerika Birleşik Devletleri
Omowunmi Sadik
Binghamton University State University Of New York, Amerika Birleşik Devletleri
Binghamton University State University Of New York, Amerika Birleşik Devletleri
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | ACS Omega (Q2) | ||
| Dergi ISSN | 2470-1343 Dergi Bilgileri (2019) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 07-2019 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 30-07-2019 |
| Cilt / Sayı / Sayfa | 4 / 7 / 12865–12871 | DOI | 10.1021/acsomega.9b00077 |
| Makale Linki | https://pubs.acs.org/doi/10.1021/acsomega.9b00077 | ||
| UAK Araştırma Alanları |
Biyokimya
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| Özet |
| The surge of resistant food pathogens is a major threat worldwide. Previous research conducted on phytochemicals has shown their antibacterial activity against pathogenic bacteria. The design of antimicrobial agents to curb pathogenic disease remains a challenge demanding critical attention. Flavonoids such as apigenin and quercetin were evaluated against Gram-positive and Gram-negative bacteria. The results indicated that the antibacterial activity of each flavonoid occurred at a different minimum inhibitory concentration. However, the antimicrobial activity results of the modified flavonoids were also reported, and it was observed that the Gram-positive bacteria were more susceptible in comparison to the Gram-negative bacteria. The cell wall structure of the Gram-positive and Gram-negative bacteria could be the main reason for the bacteria susceptibility. Modified flavonoids could be used as a suitable alternative antimicrobial agent for the treatment of infectious diseases. Our results indicated 100% inhibition of Listeria monocytogenes, Pseudomonas aeruginosa, and Aeromonas hydrophila with modified flavonoids. |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Scopus | 128 |