| Yazarlar |
Francis J Osonga
|
|
Ali Akgul
|
|
Roland Miller
|
|
Gaddi Eshun
|
Doç. Dr. İdris YAZGAN
Kastamonu Üniversitesi, Türkiye |
|
Ayfer Akgul
|
|
Omowunmi Sadik
|
| Özet |
| The surge of resistant food pathogens is a major threat worldwide. Previous research conducted on phytochemicals has shown their antibacterial activity against pathogenic bacteria. The design of antimicrobial agents to curb pathogenic disease remains a challenge demanding critical attention. Flavonoids such as apigenin and quercetin were evaluated against Gram-positive and Gram-negative bacteria. The results indicated that the antibacterial activity of each flavonoid occurred at a different minimum inhibitory concentration. However, the antimicrobial activity results of the modified flavonoids were also reported, and it was observed that the Gram-positive bacteria were more susceptible in comparison to the Gram-negative bacteria. The cell wall structure of the Gram-positive and Gram-negative bacteria could be the main reason for the bacteria susceptibility. Modified flavonoids could be used as a suitable alternative antimicrobial agent for the treatment of infectious diseases. Our results indicated 100% inhibition of Listeria monocytogenes, Pseudomonas aeruginosa, and Aeromonas hydrophila with modified flavonoids. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | ACS Omega |
| Dergi ISSN | 2470-1343 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 07-2019 |
| Cilt No | 4 |
| Sayı | 7 |
| Sayfalar | 12865 / 12871 |
| Doi Numarası | 10.1021/acsomega.9b00077 |
| Makale Linki | https://pubs.acs.org/doi/10.1021/acsomega.9b00077 |
| Atıf Sayıları | |
| SCOPUS | 68 |
