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Antimicrobial Activity of a New Class of Phosphorylated and Modified Flavonoids   
Yazarlar (7)
Francis J Osonga
Ali Akgul
Roland Miller
Gaddi Eshun
Doç. Dr. İdris YAZGAN Doç. Dr. İdris YAZGAN
Kastamonu Üniversitesi, Türkiye
Ayfer Akgul
Omowunmi Sadik
Devamını Göster
Özet
The surge of resistant food pathogens is a major threat worldwide. Previous research conducted on phytochemicals has shown their antibacterial activity against pathogenic bacteria. The design of antimicrobial agents to curb pathogenic disease remains a challenge demanding critical attention. Flavonoids such as apigenin and quercetin were evaluated against Gram-positive and Gram-negative bacteria. The results indicated that the antibacterial activity of each flavonoid occurred at a different minimum inhibitory concentration. However, the antimicrobial activity results of the modified flavonoids were also reported, and it was observed that the Gram-positive bacteria were more susceptible in comparison to the Gram-negative bacteria. The cell wall structure of the Gram-positive and Gram-negative bacteria could be the main reason for the bacteria susceptibility. Modified flavonoids could be used as a suitable alternative antimicrobial agent for the treatment of infectious diseases. Our results indicated 100% inhibition of Listeria monocytogenes, Pseudomonas aeruginosa, and Aeromonas hydrophila with modified flavonoids.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı ACS Omega
Dergi ISSN 2470-1343
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q2
Makale Dili İngilizce
Basım Tarihi 07-2019
Cilt No 4
Sayı 7
Sayfalar 12865 / 12871
Doi Numarası 10.1021/acsomega.9b00077
Makale Linki https://pubs.acs.org/doi/10.1021/acsomega.9b00077
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
SCOPUS 92
Antimicrobial Activity of a New Class of Phosphorylated and Modified Flavonoids

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