DNA protection, antioxidant, antibacterial and enzyme inhibition activities of heartwood and sapwood extracts from juniper and olive woods
Yazarlar (9)
Doç. Dr. Osman Emre ÖZKAN Kastamonu Üniversitesi, Türkiye
Gokhan Zengin
Mehmet Akca
Prof. Dr. Mehmet Cengiz BALOĞLU Kastamonu Üniversitesi, Türkiye
Dr. Öğr. Üyesi Çağrı OLGUN Kastamonu Üniversitesi, Türkiye
Prof. Dr. Ergin Murat ALTUNER Kastamonu Üniversitesi, Türkiye
Prof. Dr. Saim ATEŞ Kastamonu Üniversitesi, Türkiye
Abdurrahman Aktumsek
Hasan Vurdu
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Rsc Advances (Q2)
Dergi ISSN 2046-2069 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili Türkçe Basım Tarihi 01-2015
Kabul Tarihi Yayınlanma Tarihi 01-01-2015
Cilt / Sayı / Sayfa 5 / 89 / 72950–72958 DOI 10.1039/c5ra12302j
Makale Linki http://dx.doi.org/10.1039/c5ra12302j
Özet
In this study, DNA protective, antioxidant, antibacterial and enzyme inhibiting properties of methanol extracts obtained from juniper and olive heartwood and sapwood were determined. These extracts were tested by five antioxidant methods (DPPH scavenging, FRAP, CUPRAC, metal chelating and phosphomolybdenum). Generally, heartwood extracts of both species are more efficient for DPPH radical scavenging activity, cupric ion reducing activity, ferric reducing antioxidant power and metal chelating activity than sapwood extracts. When compared to heartwood extracts, sapwood extracts have larger inhibition zone in disk diffusion test. In addition, all extracts showed high antibacterial activity against Staphylococcus aureus. DNA protection of both extracts had a capacity to inhibit the DNA damage arisen from Fenton's reagent. The highest DNA protective activity was observed in juniper sapwood extract with 84 …
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