Synthesis and characterization of 1,3,4-thiadiazole compounds derived from 4-phenoxybutyric acid for antimicrobial activities
Yazarlar (6)
Prof. Dr. Halit MUĞLU Kastamonu Üniversitesi, Türkiye
Prof. Dr. Nesrin ŞENER Kastamonu Üniversitesi, Türkiye
Hamza Ahmed Mohammad Emsaed
Kastamonu Üniversitesi, Türkiye
Kastamonu Üniversitesi, Türkiye
Prof. Dr. Sevil Özkınalı Hitit University, Türkiye
Doç. Dr. Osman Emre ÖZKAN Kastamonu Üniversitesi, Türkiye
Prof. Dr. Mahmut GÜR Kastamonu Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Journal of Molecular Structure (Q3) | ||
| Dergi ISSN | 0022-2860 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2018 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-12-2018 |
| Cilt / Sayı / Sayfa | 1174 / 1 / 151–159 | DOI | 10.1016/j.molstruc.2018.03.116 |
| Makale Linki | http://dx.doi.org/10.1016/j.molstruc.2018.03.116 | ||
| Özet |
| New 1,3,4-thiadiazole compounds were synthesized through the cyclization reaction of 4-phenoxybutyric acid and N-phenylthiosemicarbazide derivatives with phosphorous oxychloride. The structures of 1,3,4-thiadiazole compounds (I–XII) were clarified using spectroscopic methods such as FT-IR, 1H NMR, and 13C NMR. Moreover, their antibacterial activities were tested against gram negative bacteria (Salmonella enteritidis, Salmonella typhimurium, Enterobacter aerogenes, Salmonella infantis, Salmonella kentucky, Escherichia coli) and gram positive bacteria (Staphylococcus aureus, Bacillus subtilis, Enterococcus durans) using a disk diffusion method. An antifungal activity experiment was further carried out against Candida albicans using the disk diffusion method. While these compounds presented antibacterial activity against S. aureus, they did not show antimicrobial activity against gram negative (E. coli, E … |
| Anahtar Kelimeler |
| 1,3,4-Thiadiazole | Antimicrobial activity | IR and NMR spectroscopies |
Science Direct
Synthesis and characterization of 1,3,4-thiadiazole compounds derived from 4-phenoxybutyric acid for antimicrobial activities
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 18 |
| Scopus | 22 |
| Google Scholar | 31 |