| Yazarlar |
Doç. Dr. Halit MUĞLU
Kastamonu Üniversitesi, Türkiye |
Doç. Dr. Muhammet Serdar ÇAVUŞ
Kastamonu Üniversitesi, Türkiye |
Doç. Dr. Temel Kan BAKIR
Kastamonu Üniversitesi, Türkiye |
Hasan Yakan
Ondokuz Mayıs Üniversitesi, Türkiye |
| Özet |
| A series of new bis(thiosemicarbazones) have been synthesized from terephthalaldehyde and various thiosemicarbazides. IR, 1H NMR, 13C NMR spectroscopic methods, and elemental analysis were used to characterize the identification of the synthesized compounds. The in vitro antioxidant activity determinations were made using the 1,1-Diphenyl-2-Picryl Hydrazil (DPPH) method. The compounds exhibited very different inhibition activities with the change of groups attached to the bis(thiosemicarbazone) structure. The spectral and electronic properties of the compounds were investigated by DFT calculation. Intramolecular interactions were analyzed by QTAIM and IRI calculations. Intrinsic bond strength index values of the N–H bonds, Fukui indices and the local electron affinities of the compounds were calculated, and the relationships between the compounds and their antioxidant activity properties were investigated. The SET and HAT mechanisms in the reactions of the compounds with DPPH were affected by the concentration of the compounds, and the possible effects of the parameters supporting the dominant characteristics in these reactions were examined using theoretical data. |
| Anahtar Kelimeler |
| Antioxidant activity | Quantum-chemical calculations | Schiff bases | Spectroscopic studies | Thiosemicarbazone |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | JOURNAL OF THE INDIAN CHEMICAL SOCIETY |
| Dergi ISSN | 0019-4522 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 12-2022 |
| Cilt No | 99 |
| Sayı | 12 |
| Doi Numarası | 10.1016/j.jics.2022.100789 |
| Makale Linki | http://dx.doi.org/10.1016/j.jics.2022.100789 |
| Atıf Sayıları | |
| WoS | 3 |
| SCOPUS | 2 |
