Polar paradox revisited: analogous pairs of hydrophilic and lipophilic antioxidants in linoleic acid emulsion containing Cu(II)
Yazarlar (4)
Prof. Dr. Temel Kan BAKIR Yıldız Teknik Üniversitesi, Türkiye
Inci Sönmezoǧlu
Yıldız Teknik Üniversitesi, Türkiye
Yıldız Teknik Üniversitesi, Türkiye
Filiz Imer
Yıldız Teknik Üniversitesi, Türkiye
Yıldız Teknik Üniversitesi, Türkiye
Reşat Apak
Istanbul Üniversitesi, Türkiye
Istanbul Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of the Science of Food and Agriculture | ||
| Dergi ISSN | 0022-5142 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2013 |
| Kabul Tarihi | 25-01-2013 | Yayınlanma Tarihi | 20-03-2013 |
| Cilt / Sayı / Sayfa | 93 / 10 / 2478–2485 | DOI | 10.1002/jsfa.6063 |
| Makale Linki | http://doi.wiley.com/10.1002/jsfa.6063 | ||
| UAK Araştırma Alanları |
Fiziksel Kimya
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| Özet |
| Background: Literature data are scarce on the activities of analogous pairs of hydrophilic and lipophilic antioxidants related to the 'polar paradox' distinguishing antioxidants based on their partitioning between lipids and water. The peroxidation of linoleic acid (LA) in the presence of either Cu(II) ions alone or Cu(II) ions combined with Trolox (TR), ascorbic acid (AA), hydroquinone (HQ) and gallic acid (GA), as hydrophilic antioxidants, or with α-tocopherol (TocH), ascorbyl palmitate (AP), tert-butyl hydroquinone (TBHQ) and propyl gallate (PG), as their respective lipophilic analogues, was investigated in aerated and incubated emulsions at 37 °C and pH 7. Results: LA peroxidation induced by Cu(II) followed pseudo-first-order kinetics with respect to the formation of primary (hydroperoxides) and secondary (aldehyde- and ketone-like) oxidation products, which were determined by ferric thiocyanate (Fe(III)-SCN) and thiobarbituric acid-reactive substances (TBARS) methods respectively. With the exception of TocH at certain concentrations, the tested compounds showed antioxidant behaviour depending on their polarities. The results were evaluated in the light of structure-activity relationships and the polar paradox. Conclusion: The results of this study partly confirm the hypothesis that the polar paradox experiences limitations in oil-in-water emulsions and that its validity is also dependent on the concentrations of the antioxidants employed. © 2013 Society of Chemical Industry. |
| Anahtar Kelimeler |
| Antioxidant protection | Copper-initiated prooxidant activity | Hydrophilic and lipophilic antioxidants | Linoleic acid peroxidation | Polar paradox |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 12 |
| Scopus | 13 |