| Yazarlar |
Doç. Dr. Temel Kan BAKIR
Kastamonu Üniversitesi, Türkiye |
İnci Sönmezoğlu
|
|
Filiz İmer
|
|
Mustafa Reşat Apak
İstanbul Üniversitesi, Türkiye |
| Özet |
| Background: Literature data are scarce on the activities of analogous pairs of hydrophilic and lipophilic antioxidants related to the 'polar paradox' distinguishing antioxidants based on their partitioning between lipids and water. The peroxidation of linoleic acid (LA) in the presence of either Cu(II) ions alone or Cu(II) ions combined with Trolox (TR), ascorbic acid (AA), hydroquinone (HQ) and gallic acid (GA), as hydrophilic antioxidants, or with α-tocopherol (TocH), ascorbyl palmitate (AP), tert-butyl hydroquinone (TBHQ) and propyl gallate (PG), as their respective lipophilic analogues, was investigated in aerated and incubated emulsions at 37 °C and pH 7. Results: LA peroxidation induced by Cu(II) followed pseudo-first-order kinetics with respect to the formation of primary (hydroperoxides) and secondary (aldehyde- and ketone-like) oxidation products, which were determined by ferric thiocyanate (Fe(III)-SCN) and thiobarbituric acid-reactive substances (TBARS) methods respectively. With the exception of TocH at certain concentrations, the tested compounds showed antioxidant behaviour depending on their polarities. The results were evaluated in the light of structure-activity relationships and the polar paradox. Conclusion: The results of this study partly confirm the hypothesis that the polar paradox experiences limitations in oil-in-water emulsions and that its validity is also dependent on the concentrations of the antioxidants employed. © 2013 Society of Chemical Industry. |
| Anahtar Kelimeler |
| Antioxidant protection | Copper-initiated prooxidant activity | Hydrophilic and lipophilic antioxidants | Linoleic acid peroxidation | Polar paradox |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Journal of the Science of Food and Agriculture |
| Dergi ISSN | 0022-5142 |
| Dergi Tarandığı Indeksler | SCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 03-2013 |
| Cilt No | 93 |
| Sayı | 10 |
| Sayfalar | 2478 / 2485 |
| Doi Numarası | 10.1002/jsfa.6063 |
| Makale Linki | http://doi.wiley.com/10.1002/jsfa.6063 |
| Atıf Sayıları | |
| SCOPUS | 13 |
