Antioxidant/prooxidant effects of a-tocopherol, quercetin and isorhamnetin on linoleic acid peroxidation induced by Cu(II) and H2O2
Yazarlar (4)
Prof. Dr. Temel Kan BAKIR Yıldız Teknik Üniversitesi, Türkiye
Inci Sönmezoǧlu
Yıldız Teknik Üniversitesi, Türkiye
Yıldız Teknik Üniversitesi, Türkiye
Filiz Imer
Yıldız Teknik Üniversitesi, Türkiye
Yıldız Teknik Üniversitesi, Türkiye
Reşat Apak
Istanbul Üniversitesi, Türkiye
Istanbul Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | International Journal of Food Sciences and Nutrition | ||
| Dergi ISSN | 0963-7486 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 10-2013 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 24-10-2013 |
| Cilt / Sayı / Sayfa | 65 / 2 / 226–234 | DOI | 10.3109/09637486.2013.845654 |
| Makale Linki | http://www.tandfonline.com/doi/full/10.3109/09637486.2013.845654 | ||
| UAK Araştırma Alanları |
Fiziksel Kimya
|
||
| Özet |
| The peroxidation of linoleic acid (LA) in the presence of copper(II) (Cu(II)) ions alone and with α-tocopherol (α-TocH) was investigated in aerated and incubated emulsions at 37°C and pH 7. Additionally, the effects of quercetin (QR) and its O-methylated derivative, isorhamnetin (IR), as potential antioxidant protectors were studied in the (Cu(II)+TocH)-induced LA peroxidation system. Cu(II)-induced LA peroxidation followed pseudo-first-order kinetics with respect to primary (hydroperoxides) and secondary (aldehydes- and ketones-like) oxidation products, which were determined by ferric thiocyanate and thiobarbituric acid-reactive substances methods, respectively. As opposed to the concentration-dependent (at 0.6 and 10.0μM) prooxidative action of α-TocH in the absence of QR and IR, the latter two compounds showed antioxidant effect over TocH. The peroxidation of LA in the presence of Cu(II)-H2O2 combination alone and with TocH, QR and IR were also investigated in aerated and incubated emulsions, where the latter three compounds exhibited antioxidant effects. © 2014 Informa UK Ltd. |
| Anahtar Kelimeler |
| Copper-initiated prooxidant activity | Hydroperoxides | Isorhamnetin | Linoleic acid peroxidation | Quercetin | Tocopherol |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 16 |
| Scopus | 20 |