| Yazarlar |
Çiğdem Albayrak Kaştaş
Sinop Üniversitesi, Türkiye |
|
Gökhan Kaştaş
Samsun Üniversitesi, Türkiye |
|
Aytaç Güder
Giresun Üniversitesi, Türkiye |
Doç. Dr. Mahmut GÜR
Kastamonu Üniversitesi, Türkiye |
Doç. Dr. Halit MUĞLU
Kastamonu Üniversitesi, Türkiye |
|
Orhan Büyükgüngör
Ondokuz Mayıs Üniversitesi, Türkiye |
| Özet |
| Two Schiff bases, namely (E)-4,6-dibromo-3-methoxy-2-[(phenylimino)methyl]phenol (1) and (Z)-2,4-dibromo-6-[(4-buthylphenylamino)methylene]-5-methoxycyclohexa-2,4-dienone (2), have been investigated by considering solvent, substituent and temperature dependence of prototropy, and scavenging activities. Experimental (X-ray diffraction, UV–vis and NMR) and computational (DFT) techniques have been used to obtain key data on prototropy and other properties of interest. X-ray and UV–vis results underline the variability in the structural preferences of the compounds with respect to the phase and solvent media conditions. This kind of tautomeric behavior has been elaborated by 1H NMR and 13C NMR experiments performed at room and low temperatures. Radical scavenging properties of two compounds have been probed for their usage potentials as therapeutic agent and ingredient in medicinal and food industries, respectively. For this purpose, three different test methods (DPPH, ABTS•+ and DMPD•+) have been used. It has been found from in vivo and in vitro studies that the compound 2 could be interesting as an active component in pharmaceutical industry or as an additive in food industry when its antiradical activity is considered. |
| Anahtar Kelimeler |
| Keto-amine | NMR | Phenol-imine | Scavenging activity | Schiff base | Tautomerism | X-ray |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Journal of Molecular Structure |
| Dergi ISSN | 0022-2860 |
| Dergi Tarandığı Indeksler | SCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 02-2017 |
| Cilt No | 1130 |
| Sayfalar | 623 / 632 |
| Doi Numarası | 10.1016/j.molstruc.2016.11.023 |
| Makale Linki | https://linkinghub.elsevier.com/retrieve/pii/S0022286016311784 |
| Atıf Sayıları | |
| SCOPUS | 18 |
