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Investigation of Respiratory Syncytial Virus (RSV) and Parainfluenza-3 (PI-3) virus by histopathological and immunohistochemical Methods in sheep and goats   
Yazarlar
Doç. Dr. Funda TERZİ Doç. Dr. Funda TERZİ
Kastamonu Üniversitesi, Türkiye
Ayşe Gül Dal Tabağ
Serdar Odacı
Yavuz Ulusoy
Bahadır Kılınç
Türkiye
Özet
Respiratory Syncytial Virus (RSV) and Parainfluenza type 3 (PI3) virus cause serious respiratory system infections in sheep and goats. It was aimed to investigate the localization and distribution of sheep and goat RSV and PI-3 in lung tissue by histopathological and immunohistochemical methods. The study material consisted of 30 sheep and 24 goat lung paraffin blocks from Samsun and its surrounding regions, which came to Samsun Control and Veterinary Research Institute between 2016-2019. Histopathological changes characterized by bronchial and bronchiolar epithelial degeneration and desquamation, interalveolar septal thickness, epithelialization of the alveolar epithelial surface and inflammatory cells in the alveolar lumen. In addition, hyperplasia of peribronchial lymphoid tissue, hyaline membrane formation and syncytial cells in alveoli were observed less frequently. Althought, bronchiolitis obliterans were not detected in any of the cases. In immunohistochemical staining, RSV antigen was detected in 50% of sheep and 54% of goats, and PI-3 antigen was detected in 40% of sheep and 50% of goats. RSV and PI-3 antigenic distribution of sheep and goats in bronchial and bronchiolar epithelium and cells debris and interalveolar septum were statistically similar (p>0.05). PI-3 antigen in goats was detected more intensely than sheep (p<0.05) in alveolar macrophages statistically. It was concluded that the localization of RSV and PI-3 antigens in sheep and goat lung tissue was detected similar by this study. In addition, it was determined that RSV and PI-3 antigens were common in sheep and goats and it was thought that vaccination should be done for protection.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayımlanan tam makale
Dergi Adı Journal of Advances in VetBio Science and Techniques
Dergi ISSN 2548-1150
Dergi Tarandığı Indeksler TR DİZİN
Makale Dili İngilizce
Basım Tarihi 04-2022
Cilt No 7
Sayı 1
Sayfalar 100 / 108
Doi Numarası 10.31797/vetbio.976306
Makale Linki https://dergipark.org.tr/en/pub/vetbio/issue/68450/976306