img
The Preventive Effects of Different Doses of Glucomannan on Experimental Aflatoxicosis in Japanese Quails   
Yazarlar
Orhan Yavuz
Türkiye
Özgür Özdemir
Selçuk Üniversitesi, Türkiye
Mustafa Ortatatlı
Selçuk Üniversitesi, Türkiye
Banu Atalay
Batman Üniversitesi, Türkiye
Fatih Hatipoğlu
Selçuk Üniversitesi, Türkiye
Doç. Dr. Funda TERZİ
Kastamonu Üniversitesi, Türkiye
Özet
This experimental study was performed to investigate whether there is a protective effect of different doses of Glucomannan using against aflatoxicosis in Japanese quail, and pathological changes and relative organ weights were compared. In the experiment, 60 one-day old male Japanese quails were used as divided into six different groups. Experimental groups were designated as Control(C), aflatoxin(A), glucomannan(GM), 2-fold dose of glucomannan(2GM), aflatoxin+glucomannan(A+GM) and aflatoxin+2-fold dose of glucomannan(A+2GM). While control group quails fed the standard ration as ad libitum, other groups were fed with the administrations additionally to standard diet respectively; 2mg/kg of aflatoxin to group A, 1g/kg of glucomannan to group GM, 2g/kg of glucomannan to group 2GM, 2mg/kg of aflatoxin and 1g/kg glucomannan to group A+GM, 2mg/kg of aflatoxin and 2g/ kg glucomannan to group A+2GM. All quails were euthanized at day 21 of the study and organs, (liver, spleen, kidney, thymus and bursa of Fabricius) were removed, weighed and subjected to routine histopathological procedures. Although any important macroscopic changes were not observed in the C, GM and 2GM groups, significant pathological changes were found in the groups of A, A+GM and A+2GM. In the A+GM group, the partial reduction in the severity of microscopic lesions were seen in liver, bursa of Fabricius, thymus and spleen, however a significant reduction in severity of lesions was noticed in A+2GM group. As a result of the study, 2g/kg of glucomannan has been found pathologically to be more effective than 1g/kg glucomannan in terms of the protection against aflatoxicosis by giving orally.
Anahtar Kelimeler
Aflatoxin | Glucomannan | Histopathology | Quail
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Brazilian Journal of Poultry Science
Dergi ISSN 1516-635X
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 07-2017
Cilt No 19
Sayı 3
Sayfalar 409 / 416
Doi Numarası 10.1590/1806-9061-2016-0349
Makale Linki https://www.scielo.br/j/rbca/a/Znq5SNFw4YD3LTnz88HXckb/?format=pdf&lang=en