Yazarlar |
Doç. Dr. Halit MUĞLU
Kastamonu Üniversitesi, Türkiye |
Hasan Yakan
Türkiye |
Doç. Dr. Temel Kan BAKIR
Kastamonu Üniversitesi, Türkiye |
Özet |
New bis(isatins-thio/carbohydrazones) based on Schiff bases were prepared from terephthalaldehyde bis-carbohydrazone and 5-substituted isatins in the presence of a drop of sulfuric acid under reflux in ethanol. Terephthalaldehyde bis(thio/carbohydrazone) was synthesized by the reaction of (thio)/carbohydrazide and terephthalaldehyde in the presence of a few drops of acetic acid under reflux in ethanol. The structures of these synthesized compounds were determined using IR, 1H NMR, and 13C NMR spectroscopy and elemental analysis. The in vitro antioxidant activity of all the compounds was determined by the 1,1-diphenyl-2-picryl hydrazyl (DPPH) free radical scavenging method. Compound 2 showed the best antioxidant activity. |
Anahtar Kelimeler |
Carbohydrazone | DPPH | Isatin | Schiff bases | Spectroscopic techniques |
Makale Türü | Özgün Makale |
Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
Dergi Adı | TURKISH JOURNAL OF CHEMISTRY |
Dergi ISSN | 1303-6130 |
Dergi Tarandığı Indeksler | SCI-Expanded |
Dergi Grubu | Q4 |
Makale Dili | İngilizce |
Basım Tarihi | 02-2020 |
Cilt No | 44 |
Sayı | 1 |
Sayfalar | 237 / 248 |
Doi Numarası | 10.3906/kim-1910-13 |
Makale Linki | http://dx.doi.org/10.3906/kim-1910-13 |