img
Synthesis, spectroscopic studies, and antioxidant activities of novel thio/carbohydrazones and bis-isatin derivatives from terephthalaldehyde     
Yazarlar
Doç. Dr. Halit MUĞLU Doç. Dr. Halit MUĞLU
Kastamonu Üniversitesi, Türkiye
Hasan Yakan
Türkiye
Doç. Dr. Temel Kan BAKIR Doç. Dr. Temel Kan BAKIR
Kastamonu Üniversitesi, Türkiye
Özet
New bis(isatins-thio/carbohydrazones) based on Schiff bases were prepared from terephthalaldehyde bis-carbohydrazone and 5-substituted isatins in the presence of a drop of sulfuric acid under reflux in ethanol. Terephthalaldehyde bis(thio/carbohydrazone) was synthesized by the reaction of (thio)/carbohydrazide and terephthalaldehyde in the presence of a few drops of acetic acid under reflux in ethanol. The structures of these synthesized compounds were determined using IR, 1H NMR, and 13C NMR spectroscopy and elemental analysis. The in vitro antioxidant activity of all the compounds was determined by the 1,1-diphenyl-2-picryl hydrazyl (DPPH) free radical scavenging method. Compound 2 showed the best antioxidant activity.
Anahtar Kelimeler
Carbohydrazone | DPPH | Isatin | Schiff bases | Spectroscopic techniques
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı TURKISH JOURNAL OF CHEMISTRY
Dergi ISSN 1303-6130
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 02-2020
Cilt No 44
Sayı 1
Sayfalar 237 / 248
Doi Numarası 10.3906/kim-1910-13
Makale Linki http://dx.doi.org/10.3906/kim-1910-13