Determination of polycyclic aromatic hydrocarbon metabolites in urine of coke oven workers in Turkey and exposure assessment
Yazarlar (3)
Doç. Dr. Nesrin İÇLİ Kastamonu Üniversitesi, Türkiye
Zeliha Kayaaltı
Ankara Üniversitesi, Türkiye
Ankara Üniversitesi, Türkiye
Tülin Söylemezoğlu
Yakın Doğu Üniversitesi, Türkiye
Yakın Doğu Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Toxicological and Environmental Chemistry (Q4) | ||
| Dergi ISSN | 0277-2248 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 02-2021 |
| Cilt / Sayı / Sayfa | 103 / 2 / 219–235 | DOI | 10.1080/02772248.2021.1945603 |
| Makale Linki | http://dx.doi.org/10.1080/02772248.2021.1945603 | ||
| UAK Araştırma Alanları |
Toksikoloji
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| Özet |
| Coke-oven workers are occupationally exposed to high concentrations of polycyclic aromatic hydrocarbons. In this study, 1-hydroxypyrene, 9-hydroxyphenantrene, and 3-hydroxybenzo[a]pyrene levels were determined in the urine of occupationally exposed coke-oven worker as markers of exposure to polycyclic aromatic hydrocarbons. The validated high-pressure liquid chromatography method with fluorescence detection was performed for metabolite analysis. Average values of 1-hydroxypyrene were 1.26 µmol/mol creatinine and of 9-hydroxyphenantrene 3.68 µmol/mol creatinine in the workers group, and 0.04 and 0.06 µmol/mol creatinine in the control group. While the average value of 3-hydroxybenzo[a]pyrene was 0.007 µmol/mol creatinine in the workers group, it was below the limit of detection in the control group. All of the mean 1-hydroxypyrene values (coke-oven workers overall mean = 1.26 μmol … |
| Anahtar Kelimeler |
| biomonitoring | occupational exposure | PAH metabolites | risk assessment | toxicity |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 2 |