Synthesis and Anticancerogenic Effect of New Generation Ruthenium-Based Nanoparticle from Homalothecium sericeum with Eco-Friendly Method
Yazarlar (8)
Nourhan Samir İstinye Üniversitesi, Türkiye
Doç. Dr. Dilşad ÖZERKAN Kastamonu Üniversitesi, Türkiye
Doç. Dr. Ferdane Danışman Kalındemirtaş Erzincan Binali Yıldırım Üniversitesi, Türkiye
İshak Afşin Kariper Erciyes Üniversitesi, Türkiye
Huri Bulut İstinye Üniversitesi, Türkiye
Prof. Dr. Dürdane Serap Kuruca İstanbul Atlas Üniversitesi, Türkiye
Prof. Dr. Ergin Murat ALTUNER Kastamonu Üniversitesi, Türkiye
Prof. Dr. Engin Ulukaya İstinye Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Pharmaceutical Innovation (Q2) | ||
| Dergi ISSN | 1872-5120 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 05-2023 |
| Cilt / Sayı / Sayfa | 18 / 2 / 756–767 | DOI | 10.1007/s12247-023-09725-6 |
| Makale Linki | http://dx.doi.org/10.1007/s12247-023-09725-6 | ||
| Özet |
| BackgroundGreen synthesis is a simple, inexpensive, and highly efficient method for the preparation of nanoparticles. In this study, ethanol extracts of Homalothecium sericeum (HOM) moss were used as reducing agents for the synthesis of biocompatible ruthenium nanoparticles (RuNPs). The ruthenium-based green synthesis method has not been used in any other work in the literature. UV–visible spectrophotometer (UV–Vis), Zetasizer, FTIR, and EDX-SEM were used to characterize the RuNPs synthesized by the green synthesis method, and their efficacy on cell viability was tested on HCT116 human colon cancer cells.MethodsUV spectroscopic measurements were used to study the release of HOM-RuNPs. Apoptosis was assessed by measuring protein expression of p53, Bax, and Bcl-2 by Western blotting. The presence of apoptosis was confirmed by double staining with Hoechst dye/propidium iodide under … |
| Anahtar Kelimeler |
| Apoptosis | Green synthesis | Homalothecium sericeum | Ruthenium nanoparticles |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 5 |
| Scopus | 5 |
| Google Scholar | 4 |