Characterization and Isolation Very Small Embryonic-Like (VSEL) Stem Cells Obtained from Various Human Hematopoietic Cell Sources.
Yazarlar (4)
Serap Erdem Kuruca İstanbul Tıp Fakültesi, Türkiye
Dolay Damla Çelik İstanbul Tıp Fakültesi, Türkiye
Doç. Dr. Dilşad ÖZERKAN Kastamonu Üniversitesi, Türkiye
Gökçe Erdemir
Istanbul Üniversitesi, Türkiye
Istanbul Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Stem Cell Reviews and Reports (Q2) | ||
| Dergi ISSN | 2629-3269 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 06-2019 |
| Cilt / Sayı / Sayfa | 15 / 5 / 730–742 | DOI | 10.1007/s12015-019-09896-1 |
| Makale Linki | https://link.springer.com/article/10.1007/s12015-019-09896-1 | ||
| Özet |
| Stem cell transplantation is one of the available treatments for leukemia, lymphoma, hereditary blood diseases and bone marrow failure. Bone marrow (BM), peripheral blood progenitor cells (PBPC), and cord blood (CB) are the predominant sources of stem cells. Recently a new type of stem cell with a pluripotent potential has been identified. These cells were named “very small embryonic like stem cells (VSELs)”. It is claimed that VSEL stem cells can be found in adult BM, peripheral blood (PB), CB and other body tissues. This study is designed to characterize and isolate VSEL stem cells from different human hematopoietic sources; CB, PB and apheresis material (PBPC). VSEL stem cells were isolated from MNC and erythrocyte layers for all materials by using centrifugation and ficoll gradient method. We determined embryonic markers by flow cytometry, immunofluorescence and western blotting methods. Results … |
| Anahtar Kelimeler |
| Apheresis | Cord blood | Peripheral blood | Pluripotent stem cell markers | Very small embryonic-like (VSEL) stem cells |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 14 |
| Scopus | 18 |
| Google Scholar | 21 |