Phytotoxic, Cytotoxic and Insecticidal Activities of Chrysophthalmum dichotomum Boiss. and Heldr.

Ayaz, Fatma; Küçükboyacı, Nurgün; BANİ, Barış; Şener, Bilge; Choudhary, Muhammad Iqbal

doi:10.5530/ijper.52.3.54

Phytotoxic, Cytotoxic and Insecticidal Activities of Chrysophthalmum dichotomum Boiss. and Heldr.

Yazarlar (5)

Doç. Dr. Fatma Ayaz Selçuk Üniversitesi, Türkiye

Nurgün Küçükboyacı
Gazi Üniversitesi, Türkiye

Prof. Dr. Barış BANİ Kastamonu Üniversitesi, Türkiye

Bilge Şener Gazi Üniversitesi, Türkiye

Muhammad Iqbal Choudhary University Of Karachi, Pakistan

Makale Türü	Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı	Indian Journal of Pharmaceutical Education and Research
Dergi ISSN	0019-5464 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler	SCI-Expanded
Makale Dili	İngilizce	Basım Tarihi	07-2018
Kabul Tarihi	–	Yayınlanma Tarihi	11-06-2018
Cilt / Sayı / Sayfa	52 / 3 / 467–471	DOI	10.5530/ijper.52.3.54
Makale Linki	http://dx.doi.org/10.5530/ijper.52.4s.105

Özet

Background: Chrysophthalmum dichotomum Boiss. and Heldr. (Asteraceae) is an endemic herbaceous plant to Southern part of Turkey. Aim: To investigate in vitro phytotoxic, cytotoxic and insecticidal activities of C. dichotomum. Methods: The MeOH extract of C. dichotomum was fractionated through subsequent solvent extractions in increasing polarity with n-hexane, chloroform and n-butanol. The MeOH extract and its fractions were evaluated for their biological acitivities using in vitro screening bioassays such as cytotoxicity on brine shrimps, phytotoxicity against Lemna minor and insecticidal activity against Rhyzopertha dominica and Tribolium castaneum. Results: The n-hexane and chloroform fractions showed significant phytotoxic activity (100 % growth inhibition) at 1000 μg/ml against L. minor. The brine shrimp lethality test revealed that the chloroform and remaining water fractions of C. dichotomum have moderate and positive lethality with LD50 values of 169.48 and 46.26 µg/mL, respectively. In addition, the chloroform and n-butanol fractions had low and moderate insecticidal activity with 20 and 40 % of mortality against Tribolium castaneum, respectively. Conclusion: This study demonstrates that C. dichotomum consists of bioactive constituents responsible for phytotoxicity, cytotoxicity on brine shrimps and insecticidal activity.

Anahtar Kelimeler

Asteraceae | Chrysophthalmum dichotomum | Cytotoxicity on brine shrimps | Insecticidal activity | Phytotoxicity against lemna minor

BM Sürdürülebilir Kalkınma Amaçları

Atıf Sayıları

Phytotoxic, Cytotoxic and Insecticidal Activities of Chrysophthalmum dichotomum Boiss. and Heldr.

Dergi Adı	Indian Journal of Pharmaceutical Education and Research
Yayıncı	Association of Pharmaceutical Teachers of India
Açık Erişim	Hayır
ISSN	0019-5464
E-ISSN	0019-5464
CiteScore	1,4
SJR	0,208
SNIP	0,371

Phytotoxic, Cytotoxic and Insecticidal Activities of Chrysophthalmum dichotomum Boiss. and Heldr.

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