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Synthesis and theoretical calculations of the 1h pyrazole 3 carboxamide and 3carboxylate derivatives    
Yazarlar
İsmail Yıldırım
Erciyes Üniversitesi, Türkiye
Prof. Dr. Fatma KANDEMİRLİ Prof. Dr. Fatma KANDEMİRLİ
Kocaeli Üniversitesi, Türkiye
Özet
The 1H-pyrazole-3-carboxylic acid 2 is obtained easily from the furan-2,3-dione 1 and phenylhydrazine and converted via reactions to its acid chloride 3 which reacts with various binucleophiles diamine derivatives 4a-i and gives the corresponding 1H-pyrazole-3-carboxamides and - 3-carboxylates 5a-i in good yields (50-90%). The structures of all new synthesized compounds were determined with the 13C NMR, 1H NMR, IR, MS spectroscopic data and elemental analyses. Most of them were compared with their previously obtained analogues. The electronic structures of the reactants, their transition states, intermediate states and final products of the reactions were investigated on the base of the AM1 method.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı HETEROCYCLIC COMMUNICATIONS
Dergi ISSN 0793-0283
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 01-2005
Cilt No 11
Sayı 3
Sayfalar 223 / 234
Doi Numarası 10.1515/HC.2005.11.3-4.223