| Yazarlar |
F Macaev
|
|
G Rusu
|
|
Pogrebnoi Serghei
|
|
Andriy Gudima
|
|
Stingaci Eugenia
|
|
Liviu Vlad
|
|
Shvets Nataly
|
Prof. Dr. Fatma KANDEMİRLİ
Kocaeli Üniversitesi, Türkiye |
|
R Reynold
|
|
Dimoglo Anatoly
|
| Özet |
| The preparation of novel 5-aryl-2-thio-1,3,4-oxadiazoles 4a-41 and the computer-aided study of their in vitro anti-tubercular activity against Mycobacterium tuberculosis H37Rv (ATCC 27294) are reported. The average accuracy of the electronic-topological method and neural network methods applied to the activity prediction in leave-one-out cross validation is 80%. © 2005 Elsevier Ltd. All rights reserved. |
| Anahtar Kelimeler |
| 5-Aryl-2-thio-1,3,4-oxadiazoles | Anti-tubercular activity | Electronic-topological method | Neural network method | Structure-activity relationships |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | BIOORGANIC & MEDICINAL CHEMISTRY |
| Dergi ISSN | 0968-0896 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 08-2005 |
| Cilt No | 13 |
| Sayı | 16 |
| Sayfalar | 4842 / 4850 |
| Doi Numarası | 10.1016/j.bmc.2005.05.011 |
| Atıf Sayıları | |
| WoS | 127 |
| SCOPUS | 141 |
| Google Scholar | 218 |
