| Yazarlar (6) |
Saraçoğlu. M
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|
Kandemirli. F
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Shvets. Nm
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|
Dimoglo
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|
A.S
|
| Özet |
| In this study we investigated the structure-activity relationships by using the Electron-Topological Method (ETM) for a class of AChE inhibitors related to tacrine (9-amino-1, 2, 3, 4-tetrahydroacridine) and 11 H-Indeno-[1, 2-b]-quinolin-10-ylamine that tetracyclic tacrine analogues, a drug currently in use for the treatment of the AD. Molecular fragments being specific for active and inactive compounds were revealed by using ETM. The result of testing showed the high ability of ETM in predicting the activity and inactivity in investigated series. |
| Anahtar Kelimeler |
| Bildiri Türü | Tebliğ/Bildiri |
| Bildiri Alt Türü | Poster Olarak Sergilenen Tebliğ (Uluslararası Kongre/Sempozyum) |
| Bildiri Niteliği | Alanında Hakemli Uluslararası Kongre/Sempozyum |
| Bildiri Dili | İngilizce |
| Kongre Adı | Chemical Physics V The fifth International Conference on Chemical Physics |
| Kongre Tarihi | 31-10-2002 / 01-11-2002 |
| Basıldığı Ülke | |
| Basıldığı Şehir |
