Evaluation of metabolic stress status in common carp (Cyprinus carpio) exposed to the fungicide folpet
 
Yazarlar (6)
Doç. Dr. Ümit Acar Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Yavuz Erden Bartın Üniversitesi, Türkiye
Doç. Dr. Burak Evren Inanan Aksaray Üniversitesi, Türkiye
Prof. Dr. Osman Sabri KESBİÇ Kastamonu Üniversitesi, Türkiye
Prof. Dr. Sevdan Yılmaz Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Prof. Dr. Ekrem Şanver Çelik Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Comparative Biochemistry and Physiology Part C Toxicology and Pharmacology (Q1)
Dergi ISSN 1532-0456 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili Türkçe Basım Tarihi 01-2023
Cilt / Sayı / Sayfa 263 / 1 / 109494–0 DOI 10.1016/j.cbpc.2022.109494
Makale Linki http://dx.doi.org/10.1016/j.cbpc.2022.109494
Özet
Among pesticides, fungicides are the most extensively used ones in agriculture and their effects on fish health and indirectly human health are needed to evaluate. Folpet has been used for over 50 years as a fungicide across the world. The mechanism of action of folpet on non-target aquatic organisms is so poorly understood and there is no available information about potential acute toxicity of folpet and its mechanism of action in non-target aquatic organisms. With this motivation, two successive experiments were set up: first, 96 h-LC50 value of folpet for common carp (Cyprinus carpio) was determined; and second, effects of different sublethal concentrations (0, 0.025, 0.50, 0.1 and 0.15 mg/L) of folpet on hematological serum biochemical blood parameters, DNA damages, expression levels of catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione S-transferase (GST), and cortisol …
Anahtar Kelimeler
Comet assay | Cyprinus carpio | Folpet | Gene expression | Genotoxicity