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Relation of vitamin D deficiency and new–onset atrial fibrillation among hypertensive patients     
Yazarlar
Ozgur Ulas Ozcan
Adalet Gurlek
Dr. Öğr. Üyesi Eren GÜRSOY Dr. Öğr. Üyesi Eren GÜRSOY
Türkiye
Demet Menekse Gerede
Cetin Erol
Özet
Vitamin D deficiency is associated with various cardiovascular disorders including hypertension, coronary artery disease, and heart failure. The renin-angiotensin-aldosterone system (RAS) axis is activated in vitamin D deficiency. The RAS axis also plays a role in the pathophysiology of atrial fibrillation (AF). We aimed to investigate whether vitamin D deficiency is a risk factor for the development of new-onset AF in hypertension. A total of 227 hypertensive patients were enrolled, of whom 137 had new-onset AF; 90 patients without AF were included in the control group. The age of the patient, left atrial diameter, and vitamin D deficiency increased the probability of new-onset AF independent from confounding factors (odds ratio [OR], 1.04; 95% confidence interval [CI], 1.01-1.08; P =.03 for age; OR, 1.88; 95% CI, 1.15-3.45; P =.03 for left atrial diameter; OR, 1.68; 95% CI, 1.18-2.64; P =.03 for vitamin D deficiency). Vitamin D deficiency is associated with new-onset AF in hypertension.
Anahtar Kelimeler
Arrhythmia | case-control study | nutrition | renin-angiotensin-aldosterone system
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION
Dergi ISSN 1933-1711
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 04-2015
Cilt No 9
Sayı 4
Sayfalar 307 / 312
Doi Numarası 10.1016/j.jash.2015.01.009
Makale Linki https://linkinghub.elsevier.com/retrieve/pii/S1933171115000145