Yazarlar |
Ozgur Ulas Ozcan
|
Adalet Gurlek
|
Dr. Öğr. Üyesi Eren GÜRSOY
Türkiye |
Demet Menekse Gerede
|
Cetin Erol
|
Özet |
Vitamin D deficiency is associated with various cardiovascular disorders including hypertension, coronary artery disease, and heart failure. The renin-angiotensin-aldosterone system (RAS) axis is activated in vitamin D deficiency. The RAS axis also plays a role in the pathophysiology of atrial fibrillation (AF). We aimed to investigate whether vitamin D deficiency is a risk factor for the development of new-onset AF in hypertension. A total of 227 hypertensive patients were enrolled, of whom 137 had new-onset AF; 90 patients without AF were included in the control group. The age of the patient, left atrial diameter, and vitamin D deficiency increased the probability of new-onset AF independent from confounding factors (odds ratio [OR], 1.04; 95% confidence interval [CI], 1.01-1.08; P =.03 for age; OR, 1.88; 95% CI, 1.15-3.45; P =.03 for left atrial diameter; OR, 1.68; 95% CI, 1.18-2.64; P =.03 for vitamin D deficiency). Vitamin D deficiency is associated with new-onset AF in hypertension. |
Anahtar Kelimeler |
Arrhythmia | case-control study | nutrition | renin-angiotensin-aldosterone system |
Makale Türü | Özgün Makale |
Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
Dergi Adı | JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION |
Dergi ISSN | 1933-1711 |
Dergi Tarandığı Indeksler | SCI-Expanded |
Makale Dili | İngilizce |
Basım Tarihi | 04-2015 |
Cilt No | 9 |
Sayı | 4 |
Sayfalar | 307 / 312 |
Doi Numarası | 10.1016/j.jash.2015.01.009 |
Makale Linki | https://linkinghub.elsevier.com/retrieve/pii/S1933171115000145 |