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Relation of vitamin D deficiency and new–onset atrial fibrillation among hypertensive patients    
Yazarlar
Ozgur Ulas Ozcan
Adalet Gurlek
Dr. Öğr. Üyesi Eren GÜRSOY
Türkiye
Demet Menekse Gerede
Cetin Erol
Özet
Vitamin D deficiency is associated with various cardiovascular disorders including hypertension, coronary artery disease, and heart failure. The renin-angiotensin-aldosterone system (RAS) axis is activated in vitamin D deficiency. The RAS axis also plays a role in the pathophysiology of atrial fibrillation (AF). We aimed to investigate whether vitamin D deficiency is a risk factor for the development of new-onset AF in hypertension. A total of 227 hypertensive patients were enrolled, of whom 137 had new-onset AF; 90 patients without AF were included in the control group. The age of the patient, left atrial diameter, and vitamin D deficiency increased the probability of new-onset AF independent from confounding factors (odds ratio [OR], 1.04; 95% confidence interval [CI], 1.01-1.08; P = .03 for age; OR, 1.88; 95% CI, 1.15-3.45; P = .03 for left atrial diameter; OR, 1.68; 95% CI, 1.18-2.64; P = .03 for vitamin D deficiency). Vitamin D deficiency is associated with new-onset AF in hypertension.
Anahtar Kelimeler
Arrhythmia,case-control study,nutrition,renin-angiotensin-aldosterone system
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Journal of the American Society of Hypertension
Dergi ISSN 1933-1711
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 04-2015
Cilt No 9
Sayı 4
Sayfalar 307 / 312
Makale Linki https://linkinghub.elsevier.com/retrieve/pii/S1933171115000145
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 23

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